Trimetazidin (trimetazidine) coated tablets 20 mg. №60

Description

Trimetazidin (trimetazidine) coated tablets 20 mg. №60

Composition

active substance: trimetazidine;

1 tablet contains trimetazidine dihydrochloride 20 mg;

Excipients: corn starch, mannitol E 421, povidone, talc, magnesium stearate, coating “SeleCoat ™” (hypromellose, polyethylene glycol (macrogol) 6000, titanium dioxide E 171), dye “Azorubin” (carmoisin) (barmoisin) E 122v event FCF »E 110.

Dosage form

Film-coated tablets.

Main physical and chemical properties: round tablets with a biconvex surface, coated with red. Two layers are visible on the fault.

Pharmacotherapeutic group

Cardiac drugs. Trimetazidine.
ATX code C01E B15.

Pharmacological properties

The drug acts on metabolic energy processes in body cells that need oxygen. Prevents a decrease in the content of adenosine triphosphoric acid in cells, which is the main source of energy. Ensures the normal operation of membrane and transmembrane channels.
Increases the body’s resistance to oxygen loss, improves the process of oxygen demand / consumption in the tissues of the heart muscle.
It has shown itself well with the support of patients with angina pectoris (reduces the frequency of attacks), increases the body’s loyalty to physical activity – reduces the frequency of surges in blood pressure.
Reduces the activity and effect of nitroglycerins on the human body.
Effectively acts on the treatment of diseases of the inner ear – reduces tinnitus, dizziness, improves hearing, and reduces the frequency of vertigo attacks.
Taking the drug has a positive effect on the functional activity of the retina.

Indications

The drug Trimetazidin is intended for prophylaxis and support in cases of angina attacks, heart diseases, disorders of the vascular system, symptomatic dizziness in diseases of the middle ear, diseases of the vascular system.
It has proven itself well in ischemic disorders of the vestibular apparatus.

Contraindications

The drug should not be taken by persons under 18 years of age, with pronounced renal failure, liver disease, lactase deficiency or intolerance, glucose and / or galactose rejection by the body.
Hypersensitivity to the main or auxiliary substances of the drug.

Application during pregnancy and lactation

It is contraindicated during pregnancy in any trimester of pregnancy, as well as during breastfeeding.

Method of administration and dosage

The drug Trimetazidin is prescribed for oral administration.
The recommended dosage is 1 tablet twice or thrice a day with meals.
Since the drug is prescribed exclusively with a doctor’s prescription, the duration of the course of treatment is determined by medical indications and the doctor’s instructions.

Overdose

Data on the facts of drug overdose have not been obtained. The effect of drug overdose has not been studied. In case of undesirable effects, it is recommended to carry out symptomatic therapy.

Side effects

Often, patients note such adverse reactions as headaches, dizziness, tremors. All side effects disappear after the end of the course of treatment or discontinuation of the drug. Less often, hot flashes are felt to the head, face, darkening in the eyes with a sharp rise, a sharp decrease in pressure.
Quite often, patients on the course note nausea, vomiting, diarrhea, pain in the abdomen and intestines, manifestations of allergic symptoms in the form of skin rash, itching, urticaria. Asthenia (weakness, fatigue) is manifested.