Description

Zotec-300 (dexibuprofen) Coated Tablets 300 mg. №10

Ingredients

Active ingredient: Dexibuprofen 300 mg per coated tablet.

Dosage

Recommended dosage: The usual dose is 300 mg once daily, or as directed by a healthcare professional.

Indications

Indicated for: Relief of mild to moderate pain, inflammation, and fever.

Contraindications

Do not use:

• In patients with a history of hypersensitivity to dexibuprofen or other NSAIDs.
• During the third trimester of pregnancy.
• In patients with active peptic ulcers.

Directions

How to use: Swallow the tablet whole with a glass of water. Do not crush or chew the tablet.

Scientific Evidence

Pharmacological effects: Dexibuprofen is a nonsteroidal anti-inflammatory drug (NSAID) that works by inhibiting the production of prostaglandins, thereby reducing pain and inflammation. It is a selective inhibitor of cyclooxygenase-2 (COX-2) and has been shown to have comparable efficacy to traditional NSAIDs with potentially fewer gastrointestinal side effects.

Clinical trials: A study published in the Journal of Pain Research demonstrated the efficacy of dexibuprofen in the management of osteoarthritis pain, showing significant improvements in pain scores and physical function compared to placebo. Another study in the European Journal of Clinical Pharmacology highlighted the favorable gastrointestinal tolerability profile of dexibuprofen compared to ibuprofen.

Additional Information

Warnings: Avoid concurrent use of dexibuprofen with other NSAIDs or anticoagulants to reduce the risk of bleeding. Long-term use may increase the risk of cardiovascular events. Consult a healthcare professional before use if pregnant, nursing, or have underlying medical conditions.

Storage: Store at room temperature away from moisture and heat. Keep out of reach of children.