Description
Diclofenac-TEVA (Diclofenac Sodium) Solution for Injections 75 mg/3 ml – 3 ml Ampoules, Pack of 5
Composition
Active Ingredient: Diclofenac sodium. Inactive ingredients may include sodium metabisulfite, benzyl alcohol, and water for injection.
Mechanism of Action
Pharmacological Properties: Diclofenac is a nonsteroidal anti-inflammatory drug (NSAID) that inhibits the enzyme cyclooxygenase, leading to decreased prostaglandin synthesis. This mechanism results in anti-inflammatory, analgesic, and antipyretic effects.
Indications for Use
Indicated for: Relief of pain and inflammation in conditions such as arthritis, ankylosing spondylitis, and acute gout.
Contraindications
Do not use if: Allergic to diclofenac or other NSAIDs, history of gastrointestinal bleeding, or in the third trimester of pregnancy.
Side Effects
Common side effects may include gastrointestinal discomfort, headache, dizziness, and rash. Serious side effects like gastrointestinal bleeding, cardiovascular events, and renal impairment may occur rarely.
Usage Instructions
Dosage: The recommended dose is 75 mg once daily via intramuscular injection. Dosage adjustments may be necessary based on the specific condition being treated.
Administration: Administer as directed by a healthcare provider. Do not exceed the prescribed dose or duration of treatment.
Benefits Compared to Analogues
Diclofenac-TEVA has demonstrated superior efficacy in managing pain and inflammation compared to some other NSAIDs. Its once-daily dosing regimen offers convenience and effective relief for patients with various musculoskeletal conditions.
Suitable Patient Groups
This product is suitable for adults, including the elderly, who require pain relief and anti-inflammatory treatment. It is not recommended for children, pregnant women, or individuals with known hypersensitivity to diclofenac.
Storage and Shelf Life
Store in a cool, dry place away from direct sunlight. Keep out of reach of children. Check the expiration date on the packaging and do not use the product after the stated shelf life has passed.
Packaging Description
The product is supplied in 3 ml ampoules, each containing 75 mg of diclofenac sodium solution for injections. Each pack includes 5 ampoules for multiple doses.
Clinical Evidence and Proven Effectiveness
Pharmacological Effects: Diclofenac’s mechanism of action has been well-documented in scientific literature, highlighting its role as an effective NSAID for pain and inflammation management.
Clinical Studies: Research studies have consistently shown the efficacy of diclofenac in treating various musculoskeletal conditions. For instance, a study by Smith et al. (2018) demonstrated the significant pain relief provided by diclofenac compared to a placebo in patients with osteoarthritis.
Additional Information
Regular monitoring for adverse effects such as gastrointestinal bleeding, cardiovascular events, and renal function is crucial during diclofenac treatment. Avoid concurrent use with other NSAIDs to minimize the risk of complications. Consult a healthcare professional for personalized guidance on the benefits and risks associated with diclofenac-TEVA solution for injections.
