Description
Diclofenak Natrium (Diclofenac) Gel 1% 40 g
Ingredients
Active Ingredient: Diclofenac Sodium 1%
Other Ingredients: Carbomer, Cocoyl Caprylocaprate, Isopropyl Alcohol, Liquid Paraffin, Perfume, Propylene Glycol, Purified Water.
Mechanism of Action
Diclofenac is a nonsteroidal anti-inflammatory drug (NSAID) that inhibits the production of prostaglandins, reducing pain and inflammation.
Pharmacological Properties
Diclofenac exerts its anti-inflammatory effects by inhibiting cyclooxygenase enzymes, thereby reducing inflammatory mediator production.
Indications for Use
Diclofenac gel is indicated for the relief of pain and inflammation in conditions such as arthritis, sprains, strains, and back pain.
Contraindications
Do not use diclofenac gel if:
- You are allergic to diclofenac or other NSAIDs.
- You have a history of asthma, urticaria, or allergic reactions to aspirin or other NSAIDs.
- You are in the third trimester of pregnancy.
Side Effects
Diclofenac gel may cause skin irritation or allergic reactions. Avoid contact with eyes and mucous membranes.
Usage Instructions
Apply a thin layer of gel to the affected area 3-4 times a day. Clean and dry the area before application. Gently massage the gel into the skin and wash hands after use.
Benefits Compared to Analogues
Clinical trials have shown that diclofenac gel provides effective pain relief and reduces inflammation in musculoskeletal conditions with a favorable safety profile compared to other topical NSAIDs.
Suitable Patient Groups
Diclofenac gel is generally well-tolerated and suitable for adults, including the elderly, for localized pain and inflammation. Consult a healthcare professional before use if pregnant or breastfeeding.
Storage and Shelf Life
Store diclofenac gel at room temperature away from moisture and heat. Check the expiration date on the packaging and do not use if expired.
Packaging Description
Diclofenac gel is available in a 40g tube for topical application.
Clinical Evidence and Proven Effectiveness
Clinical studies have shown that diclofenac gel effectively manages pain and inflammation in osteoarthritis with a positive safety profile. Research in the Journal of Clinical Rheumatology demonstrated its efficacy in osteoarthritis pain management.