Description

Clexane (enoxaparin) solution for injections syringe 20 mg. 0.2 ml. №10

Ingredients:

Each syringe contains 20 mg of enoxaparin sodium.

Dosage:

The usual dose is 1 to 1.5 mg/kg of body weight, depending on the condition being treated. Dosage may vary, so follow your healthcare provider’s instructions.

Indications:

Clexane is indicated for the prevention of blood clots in various conditions such as deep vein thrombosis and pulmonary embolism.

Contraindications:

Do not use Clexane if you are allergic to enoxaparin or heparin, or if you have active major bleeding. Consult your doctor for alternatives.

Directions:

Administer Clexane by subcutaneous injection. Rotate injection sites and do not rub the area after injection. Follow all instructions carefully.

Scientific Evidence:

Studies have shown that enoxaparin, the active ingredient in Clexane, effectively prevents blood clots with a lower risk of side effects compared to unfractionated heparin. Research published in the New England Journal of Medicine supports the efficacy of enoxaparin in various clinical settings.

Additional Information:

It is important to monitor platelet counts during treatment with Clexane to detect any signs of thrombocytopenia. Inform your healthcare provider of any unusual bleeding or bruising.

Pharmacologically, enoxaparin works by inhibiting the formation of blood clots. It interacts with antithrombin III to selectively potentiate the inhibition of factor Xa. This mechanism reduces the risk of thrombus formation.

Clexane has been compared to other anticoagulants like warfarin and has shown comparable effectiveness with a more predictable anticoagulant response and a lower risk of bleeding complications in certain patient populations.