Description
Diclofenak (Diclofenac) Solution for Injections 2.5% 3 ml. №5
Composition
- Diclofenac sodium
- Sodium metabisulfite
- Propylene glycol
- Water for injections
Mechanism of Action
Diclofenac inhibits the enzyme cyclooxygenase, reducing prostaglandin production, which plays a role in inflammation and pain.
Pharmacological Properties
Diclofenac exerts anti-inflammatory, analgesic, and antipyretic effects by inhibiting prostaglandin synthesis.
Indications for Use
Diclofenak solution for injections is indicated for pain and inflammation relief in conditions such as rheumatoid arthritis, osteoarthritis, ankylosing spondylitis, and acute gout.
Contraindications
Avoid Diclofenak injections if there is a history of allergic reactions to diclofenac or other NSAIDs, active peptic ulcer, severe heart failure, or during the third trimester of pregnancy.
Side Effects
Common side effects may include gastrointestinal disturbances, dizziness, headache, and skin reactions. Consult a healthcare provider for a complete list of side effects.
Usage Instructions
Administer 75 mg once daily by intramuscular injection. Dosage may vary based on the condition. Inject deep into the muscle and rotate sites to prevent irritation.
Benefits Compared to Analogues
Diclofenac injections have shown superior effectiveness in acute pain management compared to oral formulations, providing rapid relief and targeted action.
Suitable Patient Groups
Diclofenak injections are suitable for adults, including the elderly, for the management of inflammatory conditions. Consult a healthcare provider for pediatric use.
Storage and Shelf Life
Store Diclofenak solution for injections at room temperature, protected from light and moisture. Check the packaging for the expiration date.
Packaging Description
The product is available in 3 ml vials, packaged in boxes of 5 vials each.
Clinical Evidence and Proven Effectiveness
Diclofenac is a well-established NSAID with proven efficacy in managing pain and inflammation. Studies have demonstrated its rapid relief in arthritis and musculoskeletal disorders. Research in the Journal of Clinical Rheumatology highlighted its effectiveness over oral formulations in acute pain management. Clinical trials have shown significant pain reduction within hours, making it valuable for acute pain relief.
