Description

Diclofenak natrium (diclofenac) rectal suppositories 0.05 g. №10

Ingredients

Active ingredient: Diclofenac sodium 0.05 g per suppository.

Dosage

Adults: The usual dose is 1 suppository inserted into the rectum once or twice daily. Consult a healthcare professional for personalized dosing.

Indications

Diclofenac suppositories are indicated for the relief of pain and inflammation in conditions such as rheumatoid arthritis, osteoarthritis, and ankylosing spondylitis.

Contraindications

Do not use diclofenac suppositories if you:

• Have a history of allergic reactions to diclofenac or other NSAIDs.
• Are in the third trimester of pregnancy.
• Have active peptic ulcers or gastrointestinal bleeding.

Directions

For rectal use: Wash hands before and after use. Lie on your side and insert the suppository into the rectum. Follow the instructions provided by your healthcare provider.

Scientific Evidence

Diclofenac is a nonsteroidal anti-inflammatory drug (NSAID) with analgesic and anti-inflammatory properties. It works by inhibiting the enzyme cyclooxygenase, thereby reducing the production of prostaglandins that cause pain and inflammation.

Studies have shown the efficacy of diclofenac in managing pain and inflammation associated with various musculoskeletal conditions. Research published in the Journal of Pain Research demonstrated the superior pain relief provided by diclofenac suppositories compared to placebo in patients with osteoarthritis.

Additional Information

It is important to follow the prescribed dosage and duration of treatment to avoid potential side effects. Common side effects may include gastrointestinal discomfort, headache, and dizziness. Consult your doctor if you experience any adverse reactions.

Store the suppositories in a cool, dry place away from direct sunlight. Keep out of reach of children.