Description

Diclotol (aceclofenac) coated tablets 100 mg. №100

Ingredients:

Each coated tablet contains 100 mg of aceclofenac.

Dosage:

The usual dose is one tablet daily, preferably taken with food.

Indications:

Diclotol tablets are indicated for the relief of pain and inflammation in conditions such as osteoarthritis, rheumatoid arthritis, and ankylosing spondylitis.

Contraindications:

Do not use Diclotol if you have a history of allergic reactions to NSAIDs or if you have active peptic ulcers.

Directions:

Swallow the tablet whole with a glass of water. Do not crush or chew the tablet.

Scientific Evidence:

Aceclofenac, the active ingredient in Diclotol, has been extensively studied for its efficacy in managing pain and inflammation associated with various arthritic conditions. Clinical trials have demonstrated its superior analgesic and anti-inflammatory properties compared to other NSAIDs, with a lower risk of gastrointestinal side effects.

Additional Information:

Diclotol tablets should be stored in a cool, dry place away from direct sunlight. Keep out of reach of children. If you experience any adverse effects or allergic reactions, discontinue use and consult a healthcare professional.

Pharmacological Effects:

Aceclofenac works by inhibiting the enzyme cyclooxygenase, thereby reducing the production of prostaglandins that cause pain and inflammation. This mechanism of action helps alleviate symptoms of arthritis and related conditions, providing relief to patients.

Clinical Trials and Comparative Effectiveness:

In a comparative study published in the Journal of Rheumatology, aceclofenac was found to be more effective in improving pain and function in patients with osteoarthritis compared to other NSAIDs. The study also highlighted the favorable gastrointestinal tolerability profile of aceclofenac, making it a preferred choice for long-term use.