Description

Flogoxib (celecoxib) capsules 0.1g. №10

Ingredients

Active ingredient: Celecoxib 0.1g per capsule.

Dosage

Dosage: The usual dose is 200mg once a day or 100mg twice a day. Consult your healthcare provider for the appropriate dosage.

Indications

Indicated for: Relief of signs and symptoms of osteoarthritis, rheumatoid arthritis, ankylosing spondylitis, acute pain, and primary dysmenorrhea.

Contraindications

Do not use if: Allergic to celecoxib or other NSAIDs, have a history of allergic reactions (such as asthma, urticaria, or allergic-type reactions) to aspirin or other NSAIDs.

Directions

Take Flogoxib capsules orally with a full glass of water. It can be taken with or without food. Do not crush or chew the capsules.

Scientific Evidence

Celecoxib, the active ingredient in Flogoxib, is a selective COX-2 inhibitor that works by reducing substances in the body that cause inflammation and pain. Studies have shown that celecoxib is effective in managing pain and inflammation associated with various conditions, with a lower risk of gastrointestinal side effects compared to traditional NSAIDs.

Additional Information

It is important to follow the prescribed dosage and duration of treatment to avoid potential side effects. Inform your healthcare provider about any other medications you are taking to prevent drug interactions. If you experience any unusual symptoms while taking Flogoxib, seek medical attention immediately.

Pharmacological Effects: Celecoxib selectively inhibits cyclooxygenase-2 (COX-2), an enzyme involved in the inflammatory response. By targeting COX-2, celecoxib reduces inflammation and pain without affecting COX-1, thereby minimizing gastrointestinal side effects.

Clinical Trials: Clinical trials have demonstrated the efficacy of celecoxib in managing pain and inflammation in various conditions. A study published in the Journal of Rheumatology showed that celecoxib provided significant pain relief in patients with osteoarthritis compared to a placebo group.