Description

Nimid (nimesulide) granules 100 mg 2 g. sachet №30

Ingredients:

Each sachet contains 100 mg of nimesulide.

Dosage:

The recommended dosage is one sachet (2 g) per day. It is important to follow the instructions of your healthcare provider.

Indications:

Nimid granules are indicated for the relief of pain and inflammation in conditions such as osteoarthritis, rheumatoid arthritis, and acute musculoskeletal disorders.

Contraindications:

Do not use Nimid granules if you have a history of allergic reactions to nimesulide or other NSAIDs. It is contraindicated in patients with active peptic ulcers or gastrointestinal bleeding.

Directions:

Dissolve the contents of one sachet in a glass of water and take it orally. It is best taken with food to reduce the risk of gastrointestinal side effects.

Scientific Evidence:

Nimesulide, the active ingredient in Nimid granules, has been extensively studied for its efficacy in managing pain and inflammation. Research published in the journal *Clinical Drug Investigation* demonstrated that nimesulide is effective in reducing pain intensity and improving joint function in patients with osteoarthritis.

Additional Information:

Nimid granules provide a convenient and effective way to manage pain and inflammation associated with various conditions. It is important to use this medication as prescribed by your healthcare provider to achieve the best results.

Pharmacological Effects:

Nimesulide is a nonsteroidal anti-inflammatory drug (NSAID) with analgesic, anti-inflammatory, and antipyretic properties. It works by inhibiting the enzyme cyclooxygenase (COX), thereby reducing the production of prostaglandins that cause pain and inflammation in the body.

Clinical Trials:

Clinical trials have shown that nimesulide is as effective as other NSAIDs in relieving pain and inflammation with a lower risk of gastrointestinal side effects. A study published in the *Journal of International Medical Research* compared the efficacy and safety of nimesulide with diclofenac in patients with osteoarthritis and found similar pain relief with nimesulide and a lower incidence of gastrointestinal adverse events.

• Nimesulide is effective in managing pain and inflammation.
• It has a favorable safety profile compared to other NSAIDs.
• Clinical trials support the efficacy of nimesulide in various musculoskeletal conditions.