Description

Pentasa (mesalazine) Rectal Suppositories 1000 mg. №28

Ingredients:

Each rectal suppository contains 1000 mg of mesalazine.

Dosage:

The usual dosage is one rectal suppository to be inserted into the rectum once daily, preferably at bedtime.

Indications:

Pentasa rectal suppositories are indicated for the treatment of active ulcerative proctitis.

Contraindications:

Do not use Pentasa rectal suppositories if you are allergic to mesalazine or any other ingredients in the product.

Directions:

Before using the suppository, empty your bowels. Remove the suppository from the foil packaging and insert it gently into the rectum.

Scientific Evidence:

Studies have shown that mesalazine, the active ingredient in Pentasa, is effective in reducing inflammation in the colon and rectum.

Additional Information:

It is important to continue using Pentasa rectal suppositories as prescribed, even if you start to feel better. Consult your doctor for any concerns or questions.

Mesalazine, the key component of Pentasa rectal suppositories, exerts its pharmacological effects by inhibiting the production of inflammatory mediators in the colon. This action helps to reduce the symptoms associated with ulcerative proctitis, such as rectal bleeding and diarrhea.

Clinical trials have demonstrated the efficacy of Pentasa in inducing and maintaining remission in patients with ulcerative colitis. In a study published in the American Journal of Gastroenterology, Pentasa was found to be superior to placebo in maintaining remission over a 6-month period.