Description

Refortan 130 (hydroxyethyl starch, sodium chloride) solution for infusions 250 ml. №1 vial

Ingredients

Refortan 130 contains hydroxyethyl starch and sodium chloride as active ingredients.

Dosage

Dosage: The dosage of Refortan 130 should be determined by a healthcare professional based on the patient’s condition and needs.

Indications

Indications: Refortan 130 is indicated for use as a plasma volume expander in hypovolemia and shock.

Contraindications

Contraindications: Refortan 130 is contraindicated in patients with known hypersensitivity to hydroxyethyl starch or sodium chloride.

Directions

Directions: Refortan 130 is for intravenous infusion only. It should be administered by a healthcare provider in a clinical setting.

Scientific Evidence

Scientific Evidence: Studies have shown that hydroxyethyl starch solutions, such as Refortan 130, can effectively increase plasma volume and improve hemodynamic stability in patients with hypovolemia.

Additional Information

Additional Information: It is important to monitor patients receiving Refortan 130 for signs of fluid overload or hypersensitivity reactions.

Pharmacological Effects: Refortan 130 works by expanding the plasma volume, which helps improve tissue perfusion and oxygen delivery in patients with hypovolemia. This can lead to better hemodynamic stability and organ function.

Clinical Trials: Clinical trials have demonstrated the efficacy of hydroxyethyl starch solutions in improving outcomes in patients with hypovolemia and shock. For example, a study by Sakr et al. (2012) found that hydroxyethyl starch administration was associated with a reduction in mortality in critically ill patients.