Stoptusin-Teva (butamіratu citrate, guaifenesin) tablets №20

Description

Stoptusin-Teva (butamіratu citrate, guaifenesin) tablets №20

Composition

active substance: butamirate citrate, guaifenesin;

1 tablet contains: butamirate citrate 4 mg, guaifenesin 100 mg;

Excipients: colloidal anhydrous silica, mannitol (E 421), microcrystalline cellulose, glycerol tribegenate, magnesium stearate.

Dosage form

Tablets.

Main physical and chemical properties: round tablets, white with a fracture line on one side.

Pharmacotherapeutic group

Combination preparations containing antitussives and expectorants.
ATX code R05F B02.

Pharmacological properties

Combined drug that has antitussive, mucolytic and expectorant action. Butamirate dihydrogen citrate belongs to the non-opioid antitussives of peripheral action. It has a local anesthetic effect on nerve endings that transmit upward signals of irritation from the respiratory tract. Unlike opioid antitussives, it does not cause a central inhibitory effect, does not depress the respiratory center, does not cause dependence.
The antitussive effect of dihydrogen citrate butamirate is supplemented by the expectorant action of guaifenesin. Guaifenesin has secretolytic (by directly enhancing the secretion of bronchial glands and stimulating the elimination of acidic glycoproteins from acinar cells) and secretomotor properties (reduces the viscosity of sputum and facilitates the evacuation of mucus and its cough).

Indication

Dry irritable paroxysmal cough of various origins.

Contraindication

Hypersensitivity to any components of the drug, myasthenia gravis, I trimester of pregnancy. Stoptusin ‑ Teva should not be used in children under 12 years of age.

Method of application and dosage

Adhere to the dosage depending on the patient’s body weight:

• up to 50 kg – ½ tablets 4 times a day;
• 50-70 kg – 1 tablet 3 times a day;
• 70-90 kg – 1 and ½ tablets 3 times a day;
• from 90 kg – 2 tablets 3 times a day.

The interval between individual receptions should be 4-6 hours. The tablet can be divided in half.

The drug Stoptusin-Teva tablets is recommended for use after meals, drinking plenty of fluids (water, tea, juice).

Children

The drug should be used in children over 12 years of age according to the indications.

Overdose

Overdose is dominated by signs of toxic effects of guaifenesin – drowsiness, muscle weakness, nausea, vomiting, diarrhea, dizziness, hypotension. X-ray negative urolithiasis is possible.
There is no specific antidote.
Treatment: gastric lavage, administration of activated charcoal, symptomatic therapy aimed at maintaining the functions of the cardiovascular and respiratory systems, renal function and maintaining electrolyte balance.

Side effects

If you follow the recommended dosage, patients tolerate the drug well. Side effects usually disappear after reducing the dose.

• From the metabolism: lack of appetite.
• From the nervous system: headache, drowsiness.
• From the respiratory system: shortness of breath.
• Hearing impairment and vestibular disorders: dizziness.
• From the gastrointestinal tract: discomfort in the digestive tract, nausea, stomach pain, vomiting, diarrhea. If you experience stomach discomfort or other unusual effects, you should stop using the drug and consult a doctor.
• From the skin and subcutaneous tissue: allergic reactions, including anaphylactic shock; angioneurotic edema, skin rash, itching, urticaria, exanthema.
• From the urinary system: urolithiasis.