Description
Zotec-300 (Dexibuprofen) Coated Tablets 300 mg. №10
Ingredients
- Active ingredient: Dexibuprofen 300 mg per coated tablet.
Dosage
- Recommended dosage: The usual dose is 300 mg once daily, or as directed by a healthcare professional.
Indications
- Indicated for: Zotec-300 is used to relieve mild to moderate pain, inflammation, and fever.
Contraindications
- Do not use in:
- Patients with a history of hypersensitivity to dexibuprofen or other NSAIDs.
- During the third trimester of pregnancy.
- Patients with active peptic ulcers.
Directions
- How to use: Swallow the Zotec-300 tablet whole with a glass of water. Do not crush or chew the tablet.
Scientific Evidence
- Pharmacological effects: Dexibuprofen is a nonsteroidal anti-inflammatory drug (NSAID) that inhibits the production of prostaglandins, reducing pain and inflammation. It selectively inhibits cyclooxygenase-2 (COX-2) and has shown efficacy similar to traditional NSAIDs with potentially fewer gastrointestinal side effects.
- Clinical trials:
- A study in the Journal of Pain Research demonstrated dexibuprofen’s efficacy in managing osteoarthritis pain, with significant improvements in pain scores and physical function compared to placebo.
- Research in the European Journal of Clinical Pharmacology highlighted dexibuprofen’s favorable gastrointestinal tolerability profile compared to ibuprofen.
Additional Information
- Warnings: Avoid concurrent use of dexibuprofen with other NSAIDs or anticoagulants to reduce bleeding risk. Long-term use may increase cardiovascular event risk. Consult a healthcare professional before use if pregnant, nursing, or have underlying medical conditions.
- Storage: Store Zotec-300 at room temperature away from moisture and heat. Keep out of reach of children.
