Description

Dexapos (Dexamethasone) Eye Drops 1 mg/ml. 5 ml

Ingredients

Active ingredient: Dexamethasone 1 mg/ml.
Inactive ingredients: Benzalkonium chloride, sodium chloride, sodium hydroxide, and water for injection.

Mechanism of Action

Dexamethasone, a potent corticosteroid, exerts its pharmacological effects by inhibiting the production of inflammatory mediators, such as prostaglandins and leukotrienes. It suppresses the migration of leukocytes to the site of inflammation and reduces edema, thereby alleviating symptoms associated with ocular inflammation.

Pharmacological Properties

Dexamethasone possesses anti-inflammatory, immunosuppressive, and vasoconstrictive properties. It modulates gene expression to inhibit the synthesis of pro-inflammatory proteins, leading to a decrease in inflammation and associated symptoms.

Indications for Use

Indicated for: Treatment of inflammatory conditions of the eye when a steroid is deemed appropriate. Dexapos is prescribed for conditions such as uveitis, conjunctivitis, and keratitis where inflammation plays a significant role in the pathogenesis of the disease.

Contraindications

Do not use Dexapos if you have:

• Known hypersensitivity to dexamethasone or any other ingredients.
• Active fungal, viral, or bacterial eye infections.
• Diagnosed glaucoma.

Side Effects

Common side effects of Dexapos may include increased intraocular pressure, blurred vision, burning or stinging sensation upon instillation, and ocular discomfort. Prolonged use of corticosteroids in the eye may also lead to the development of cataracts or secondary infections.

Usage Instructions

Dosage: Instill 1 to 2 drops into the affected eye(s) every 4 to 6 hours. Consult a healthcare professional for proper usage instructions.

Benefits Compared to Analogues

Dexapos offers a potent anti-inflammatory effect with a lower risk of systemic absorption compared to some other corticosteroid eye drops. Its formulation allows for targeted treatment of ocular inflammation while minimizing the potential for systemic side effects.

Suitable Patient Groups

Dexapos is suitable for use in adult patients and pediatric populations over the age of 6 years. Special caution should be exercised when prescribing Dexapos to elderly individuals or patients with pre-existing conditions such as diabetes or hypertension.

Storage and Shelf Life

Store Dexapos eye drops at room temperature away from direct sunlight and moisture. Do not freeze. The shelf life of Dexapos is typically indicated on the packaging and should be strictly adhered to for optimal efficacy.

Packaging Description

Dexapos is available in a 5 ml sterile dropper bottle for ophthalmic use. The packaging should be kept sealed when not in use to prevent contamination and maintain the sterility of the product.

Scientific Evidence

Dexapos (dexamethasone) eye drops have shown significant efficacy in reducing inflammation and symptoms associated with various ocular conditions.

Studies have demonstrated the anti-inflammatory and immunosuppressive properties of dexamethasone, which make it a valuable treatment option for inflammatory eye conditions. Clinical trials have shown that dexamethasone eye drops can effectively reduce swelling, redness, and discomfort in patients with conditions such as uveitis and conjunctivitis.

Additional Information

It is important to follow the prescribed dosage and duration of treatment to avoid potential side effects associated with prolonged corticosteroid use. Dexapos should not be used for viral infections of the eye, as it may exacerbate the condition.

Consult your healthcare provider if you experience any adverse reactions or if your symptoms worsen while using Dexapos eye drops.