Description

Abipim (Cefepime) Powder for Injections 1000 mg. №1

Composition

Active Ingredient: Cefepime. Inactive ingredients may include mannitol and sodium carbonate.

Mechanism of Action

Pharmacological Properties: Cefepime, a fourth-generation cephalosporin, exerts its antibacterial effects by inhibiting bacterial cell wall synthesis. It demonstrates enhanced activity against many resistant organisms.

Indications for Use

Indications: Abipim is indicated for the treatment of moderate to severe infections caused by susceptible bacteria.

Contraindications

Contraindications: Avoid the use of Abipim in individuals with a known allergy to cefepime or other cephalosporins.

Side Effects

Side Effects: Common side effects may include nausea, vomiting, diarrhea, and rash. While severe allergic reactions are rare, they are possible.

Usage Instructions

Dosage: The typical adult dosage is 1 to 2 grams every 12 hours. Adjustments in dosage may be necessary depending on the infection’s severity.

Administration: Abipim is designated for intravenous use only. Prior to administration, it must be reconstituted and diluted.

Benefits Compared to Analogues

Advantages: Abipim provides a wide spectrum of activity against both Gram-positive and Gram-negative bacteria, making it a valuable choice for managing various infections.

Suitable Patient Groups

Population Suitability: Abipim is appropriate for use in adults and pediatric patients. Dosage adjustments may be required for elderly individuals and those with renal impairment.

Storage and Shelf Life

Storage: Adhere to the manufacturer’s storage guidelines. Do not use the product beyond the expiration date specified on the packaging.

Packaging Description

Packaging: Abipim is supplied as a powder for injections in single-dose vials, each containing 1000 mg of cefepime.

Clinical Evidence and Proven Effectiveness

Effectiveness: Clinical trials have demonstrated the efficacy of Abipim (cefepime) in treating various bacterial infections, including pneumonia, urinary tract infections, and intra-abdominal infections.