Description

Aladin (amlodipine besylate) Tablets 10 mg. №50

Composition

Active Ingredient: Amlodipine besylate 10 mg per tablet.

Mechanism of Action

Amlodipine besylate, a calcium channel blocker, acts by relaxing blood vessels to facilitate improved heart pumping and decreased cardiac workload, thereby reducing blood pressure and enhancing coronary blood flow to mitigate angina risks.

Pharmacological Properties

Amlodipine besylate in Aladin tablets functions as a calcium channel blocker, exerting vasodilatory effects, enhancing cardiac efficiency, and decreasing blood pressure, ultimately reducing the incidence of angina attacks.

Indications for Use

Indications: Aladin tablets are recommended for managing hypertension and chronic stable angina.

Contraindications

Contraindications: Avoid Aladin tablets if hypersensitive to amlodipine or any other components in the formulation.

Side Effects

Common side effects may include dizziness, peripheral edema, and flushing. Serious but rare side effects may encompass hypotension, palpitations, and hepatotoxicity. Consult a healthcare provider promptly if any adverse reactions occur.

Usage Instructions

Dosage: The typical dose is 5-10 mg once daily. Seek medical advice for personalized dosing.

Administration: Orally ingest Aladin tablets with or without food following healthcare provider directives.

Benefits Compared to Analogues

Aladin tablets offer comparable efficacy to other antihypertensive agents in reducing blood pressure levels, with the added advantage of potentially improving coronary blood flow and decreasing angina occurrence.

Suitable Patient Groups

Aladin tablets are suitable for adult patients, including the elderly, who require blood pressure management and angina symptom relief. Consult a healthcare professional for pediatric use.

Storage and Shelf Life

Store Aladin tablets in a cool, dry place away from children’s reach. Adhere to the expiration date indicated on the packaging.

Packaging Description

Aladin tablets are packaged in a container with 50 tablets, each containing 10 mg of amlodipine besylate.

Clinical Evidence and Proven Effectiveness

Studies have demonstrated the efficacy of amlodipine besylate in Aladin tablets for reducing blood pressure and angina frequency. Notably, a meta-analysis in the Journal of Hypertension affirmed amlodipine’s comparable efficacy with other antihypertensive agents in lowering blood pressure levels.

In a randomized controlled trial in the American Journal of Cardiology, amlodipine exhibited superior blood pressure reduction compared to placebo. Furthermore, a study in the European Heart Journal illustrated amlodipine’s equivalence to alternative antihypertensive medications in reducing cardiovascular events.