Description

Allopurinol (allopurinol) tablets 0.1 №50

Ingredients

Active ingredient: Allopurinol 100mg per tablet.

Dosage

Dosage: The usual starting dose is 100-200 mg per day, which may be increased gradually until the desired response is achieved.

Indications

Indications: Allopurinol is indicated for the management of gout and certain types of kidney stones.

Contraindications

Contraindications: Do not use in patients with hypersensitivity to allopurinol or its components.

Directions

Directions: Take this medication by mouth with or without food as directed by your doctor, usually once daily.

Scientific Evidence

Allopurinol works by inhibiting xanthine oxidase, an enzyme involved in the production of uric acid. By lowering uric acid levels in the body, allopurinol helps prevent gout attacks and the formation of uric acid stones.

Studies have shown that allopurinol is effective in reducing serum uric acid levels and preventing gout flares. Research published in the American Journal of Medicine demonstrated that allopurinol therapy significantly reduced the frequency of gout attacks in patients with hyperuricemia.

Additional Information

• Warnings: It is important to stay well-hydrated while taking allopurinol to prevent kidney stones.
• Side Effects: Common side effects may include skin rash, drowsiness, or upset stomach.

Allopurinol has been a cornerstone in the management of gout for decades and is considered a first-line therapy for hyperuricemia. Its effectiveness in reducing uric acid levels and preventing gout attacks has been well-documented in clinical practice and supported by scientific research.

Clinical trials have shown that allopurinol not only treats acute gout but also has a preventive effect, reducing the frequency and severity of gout attacks over time. Its safety profile and cost-effectiveness make it a preferred choice for long-term management of gout and hyperuricemia.