Description

Allopurinol Tablets

Composition

Active ingredient: Allopurinol 100mg per tablet.

Mechanism of Action

Allopurinol works by inhibiting xanthine oxidase, an enzyme involved in the production of uric acid. By lowering uric acid levels in the body, allopurinol helps prevent gout attacks and the formation of uric acid stones.

Pharmacological Properties

Allopurinol is a xanthine oxidase inhibitor that reduces the production of uric acid, thereby lowering serum uric acid levels.

Indications for Use

Allopurinol is indicated for the management of gout and certain types of kidney stones.

Contraindications

Do not use allopurinol in patients with hypersensitivity to allopurinol or its components.

Side Effects

• Skin rash
• Drowsiness
• Upset stomach

Usage Instructions

Dosage: The usual starting dose is 100-200 mg per day, which may be increased gradually until the desired response is achieved.

Directions: Take this medication by mouth with or without food as directed by your doctor, usually once daily.

Benefits Compared to Analogues

Allopurinol has been a cornerstone in the management of gout for decades and is considered a first-line therapy for hyperuricemia. Its effectiveness in reducing uric acid levels and preventing gout attacks has been well-documented in clinical practice.

Suitable Patient Groups

Allopurinol is suitable for adults of all ages. Dosage adjustments may be necessary in elderly patients or those with impaired renal function.

Storage and Shelf Life

Store allopurinol tablets in a cool, dry place away from moisture and sunlight. Check the expiration date on the packaging and do not use the product beyond that date.

Packaging Description

Allopurinol tablets are typically packaged in blister packs of 50 tablets each.

Clinical Evidence and Proven Effectiveness

Allopurinol therapy has shown significant reduction in serum uric acid levels and frequency of gout attacks. Studies published in reputable medical journals, such as the American Journal of Medicine, have demonstrated the efficacy of allopurinol in gout management.