Description

Amiodarone (Amiodarone Hydrochloride) Tablets 0.2 g. №30

Ingredients

Active ingredient: Amiodarone hydrochloride. Inactive ingredients may include lactose, povidone, magnesium stearate, and colloidal silicon dioxide.

Dosage

Dosage: The usual adult dose is **200-400 mg** daily, taken as directed by a healthcare provider. Dosage may vary based on individual patient needs and medical condition.

Indications

Indications: Amiodarone is indicated for the treatment of various types of irregular heartbeats (arrhythmias), including ventricular fibrillation and ventricular tachycardia.

Contraindications

Contraindications: Do not use Amiodarone if you have a known hypersensitivity to any of the ingredients, severe sinus node dysfunction, or certain types of heart block.

Directions

Directions: Take this medication by mouth with or without food, as directed by your doctor. Do not stop taking this medication without consulting your healthcare provider.

Scientific Evidence

Amiodarone has been extensively studied for its efficacy in managing various cardiac arrhythmias. Research published in the *New England Journal of Medicine* has shown that Amiodarone is effective in reducing the recurrence of atrial fibrillation compared to placebo.

Additional Information

It is important to have regular check-ups while taking Amiodarone to monitor your heart rhythm and liver function. Inform your doctor about any other medications or supplements you are taking to avoid potential drug interactions.

Pharmacological Effects: Amiodarone works by prolonging the action potential duration and refractory period of cardiac tissues, thereby stabilizing the heart’s electrical activity and preventing abnormal rhythms.

Clinical Trials: Clinical trials have demonstrated the effectiveness of Amiodarone in reducing mortality in patients with ventricular arrhythmias. A study published in the *Journal of the American College of Cardiology* showed a significant decrease in sudden cardiac death rates with Amiodarone therapy.