Amitriptyline (amityptilline) hydrochloride solution for injections 10 mg/ml. ampoules 2 ml. №10

active ingredient: amitriptyline;

1 ml of solution contains amitriptyline hydrochloride in terms of amitriptyline 10 mg;

excipients: glucose, water for injections.

Solution for injections.

Main physical and chemical properties: colorless transparent liquid.

Antidepressants. Non-selective inhibitors of the reverse neuronal uptake of monoamines. ATX code N06A A09.

Amitriptyline is a tricyclic antidepressant, a non-selective inhibitor of neuronal reuptake of monoamines. Has a pronounced thymoleptic effect, belongs to the group of large antidepressants. The thymoleptic effect is combined with a pronounced sedative effect. It also has antiserotonin, antihistaminic and anticholinergic effects.

• Endogenous depression, including a depressive episode, recurrent depressive disorder;
• bipolar affective disorder, current depressive episode.

Hypersensitivity to amitriptyline or any of the components of the drug. Glaucoma, prostate hypertrophy, bladder atony.

A recent myocardial infarction. Any kind of blockages or heart rhythm disturbances, as well as insufficiency of coronary arteries.

The simultaneous appointment of amitriptyline and MAOIs is contraindicated due to the development of serotonin syndrome (a combination of symptoms, which may include anxiety, confusion, tremors, myoclonus, and hyperthermia).

Treatment with the use of amitriptyline can be started 14 days after stopping the use of irreversible non-selective MAOIs, as well as at least 1 day after stopping the use of the reversible drugs moclobemide and selegiline.