Description

Anaprilin (propranolol hydrochloride) tablets 0.01 №50

Ingredients:

Each tablet contains propranolol hydrochloride 0.01 mg.

Dosage:

The usual dose is 40 mg to 240 mg per day, depending on the condition being treated. Dosage should be individualized based on the patient’s response.

Indications:

Anaprilin tablets are indicated for the management of hypertension, angina pectoris, and cardiac arrhythmias. It is also used in the prevention of migraine headaches.

Contraindications:

Do not use Anaprilin if you have asthma, bradycardia, or heart block. It is contraindicated in patients with severe heart failure.

Directions:

Take Anaprilin tablets orally with or without food as directed by your doctor. Do not suddenly stop taking this medication without consulting your healthcare provider.

Scientific Evidence:

Propranolol, the active ingredient in Anaprilin, is a non-selective beta-blocker that works by blocking the action of adrenaline on beta receptors in the heart. This results in decreased heart rate, blood pressure, and oxygen demand by the heart. Several studies have demonstrated the efficacy of propranolol in the management of hypertension, angina, and arrhythmias.

Additional Information:

It is important to monitor blood pressure and heart rate regularly while taking Anaprilin. This medication may interact with other drugs, so inform your doctor about all the medications you are taking. Avoid alcohol consumption while on Anaprilin as it may increase the risk of side effects.

Pharmacological Effects:

Propranolol hydrochloride, the active ingredient in Anaprilin, exerts its pharmacological effects by blocking beta-adrenergic receptors. This action results in decreased heart rate, reduced myocardial contractility, and lowered blood pressure. Additionally, propranolol reduces the release of renin from the kidneys, further contributing to its antihypertensive effects.

Clinical Trials and Comparative Effectiveness:

Clinical trials have shown that propranolol is effective in the management of various cardiovascular conditions, including hypertension and angina. In comparative studies, propranolol has been found to be equally or more effective than other beta-blockers in controlling blood pressure and reducing the frequency of angina attacks. Additionally, propranolol has been shown to be beneficial in the prevention of migraine headaches.

Overall, Anaprilin (propranolol hydrochloride) tablets 0.01 №50 offer a well-established treatment option for cardiovascular conditions, supported by scientific evidence and clinical trials.