Description
Anaprilin (Propranolol Hydrochloride) Tablets 0.04 №50
Ingredients
Active ingredient: Propranolol hydrochloride
Mechanism of Action
Propranolol hydrochloride, the active component of Anaprilin, is a non-selective beta-blocker that antagonizes beta-adrenergic receptors. By inhibiting the effects of catecholamines like adrenaline, it reduces cardiac workload, oxygen consumption, and sympathetic nervous system activity.
Pharmacological Properties
Propranolol hydrochloride exerts antianginal, antihypertensive, and antiarrhythmic effects through its negative chronotropic and inotropic actions on the heart. It also decreases peripheral vascular resistance, leading to reduced blood pressure.
Indications for Use
Anaprilin is indicated for the management of hypertension, angina pectoris, and cardiac arrhythmias. It is prescribed to control heart rate, reduce myocardial oxygen demand, and stabilize irregular heart rhythms.
Contraindications
Contraindications to Anaprilin include bronchial asthma, severe bradycardia, heart block greater than the first degree, and cardiogenic shock. Patients with these conditions should not use this medication due to the risk of exacerbation or adverse effects.
Side Effects
Common side effects of Anaprilin may include fatigue, dizziness, bradycardia, hypotension, and gastrointestinal disturbances. Rare but serious adverse reactions such as bronchospasm, heart failure, and depression may occur and require immediate medical attention.
Usage Instructions
Dosage: The typical dose of Anaprilin is 0.04 mg taken orally 2-3 times daily, with adjustments based on individual response and medical advice. The tablets should be swallowed whole with a glass of water, without crushing or chewing.
Benefits Compared to Analogues
Anaprilin offers advantages over other beta-blockers by providing a balanced profile of beta-adrenergic blockade, making it suitable for a wide range of cardiovascular conditions. Its efficacy in reducing mortality post-heart attack and improving quality of life in heart failure patients sets it apart from similar medications.
Suitable Patient Groups
Anaprilin can be used in adult patients, including the elderly, with caution and appropriate monitoring. Its safety and efficacy in pediatric populations have not been established, so its use in children is limited to specific medical conditions under close medical supervision.
Storage and Shelf Life
Anaprilin tablets should be stored in a cool, dry place away from direct sunlight and moisture. The shelf life of the product is typically indicated on the packaging and should be checked before use to ensure potency and safety.
Packaging Description
Anaprilin tablets are usually packaged in blister packs of 50 tablets each, with clear labeling of the active ingredient, dosage strength, and manufacturer information. The packaging is designed to protect the tablets from environmental factors and maintain their integrity until use.
