$32.60
Manufacturer: Poland
Vitamin D3 is an active anti-rachitic factor. The most important function of vitamin D is the regulation of calcium and phosphate metabolism, promotes proper mineralization and growth of the skeleton.
Vitamin D3 is the natural form of vitamin D found in animals and humans. Compared with vitamin D2, it is characterized by activity, 25% higher.
It is necessary for the functioning of the parathyroid glands, intestines, kidneys and the skeletal system. It plays a significant role in the absorption of calcium and phosphate from the intestines, in the transport of mineral salts and in the process of bone calcification, regulates the excretion of calcium and phosphate by the kidneys. The concentration of calcium ions affects a number of important biochemical processes that determine the maintenance of skeletal muscle tone, participate in the conduction of nervous excitation and affect blood coagulation. Vitamin D3 is also involved in the functioning of the immune system, affects the production of lymphokines.
Description
Ingredients
active ingredient: cholecalciferol;
1 ml (approximately 30 drops) of solution contains 15,000 IU of cholecalciferol (1 drop contains approximately 500 IU of vitamin D3);
excipients: macrogolglycerol ricinoleate; sucrose; sodium phosphate dodecahydrate; citric acid monohydrate, anise flavor; benzyl alcohol; purified water.
Dosage form
Aqueous solution for oral administration.
Basic physical and chemical properties: colorless transparent liquid with an anise smell and taste. The presence of opalescence in the preparation is allowed.
Pharmacotherapeutic group
Vitamins. Vitamin D preparations and its analogues. ATX code A11C C05.
Pharmacodynamics
Vitamin D3 is an active anti-rachitic factor. The most important function of vitamin D is the regulation of calcium and phosphate metabolism, promotes proper mineralization and growth of the skeleton.
Vitamin D3 is the natural form of vitamin D found in animals and humans. Compared with vitamin D2, it is characterized by activity, 25% higher.
It is necessary for the functioning of the parathyroid glands, intestines, kidneys and the skeletal system. It plays a significant role in the absorption of calcium and phosphate from the intestines, in the transport of mineral salts and in the process of bone calcification, regulates the excretion of calcium and phosphate by the kidneys. The concentration of calcium ions affects a number of important biochemical processes that determine the maintenance of skeletal muscle tone, participate in the conduction of nervous excitation and affect blood coagulation. Vitamin D3 is also involved in the functioning of the immune system, affects the production of lymphokines.
The lack of vitamin D3 in food, the weakening of its absorption, calcium deficiency, as well as the lack of exposure to sunlight during the period of rapid growth of the child lead to rickets, and in adults – to osteomalacia, in pregnant women – before the onset of symptoms of tetany and non-formation of tooth enamel in newborns.
Women in the menopausal period, who often suffer from osteoporosis, due to hormonal disorders, it is necessary to increase the dose of vitamin D3.
Indications
- prevention of rickets;
- prevention of vitamin D3 deficiency in high-risk groups without malabsorption;
- prevention of rickets in premature newborns;
- prevention of vitamin D3 deficiency in malabsorption;
- treatment of rickets and osteomalacia;
- supportive treatment of osteoporosis;
- treatment of hypoparathyroidism.
Contraindications
Hypersensitivity to the components of the drug, hypercalcemia and / or hypercalciuria, hypervitaminosis D, sarcoidosis, renal failure, nephrolithiasis, tuberculosis. Pseudohypoparathyroidism (requirement for vitamin D may be lower than during normal vitamin sensitivity). Taking vitamin D can lead to an overdose. In such situations, vitamin D in other dosage forms should be used in order to make it easier to control the concentration. The drug is contraindicated in patients with rare hereditary fructose intolerance, glucose-galactose malabsorption or sucrase-isolmaltase deficiency.
Dosage and administration
Apply orally.
Prevention of rickets: the recommended dose is 1 drop (about 500 IU of vitamin D3) per day.
Prevention of vitamin D3 deficiency in high-risk patients without malabsorption: the recommended dose is 1 drop (about 500 IU of vitamin D3) per day.
For maintenance treatment of osteoporosis, the recommended dose is 2 drops (about 1000 IU of vitamin D3) per day.
Prevention of rickets in premature newborns: the dose is determined by the doctor. The general recommended dose is 2 drops (about 1000 IU of vitamin D3) per day.
Prevention of vitamin D3 deficiency in malabsorption : the dose is determined individually by the doctor. The general recommended dose is 6-10 drops (about 3000-5000 IU of vitamin D3) drops per day.
Treatment of rickets and osteomalacia: the dose is determined individually by the doctor, depending on the course and severity of the disease. The general recommended dose for treating vitamin D3 deficiency in infants and children is 2-10 drops (about 1000-5000 IU of vitamin D3) per day. The dose in the treatment of vitamin D3 deficiency is determined individually, depending on the course and severity of the disease.
Treatment of hypoparathyroidism: the recommended dose depends on the level of calcium in the blood serum and is 20-40 drops (about 10,000-20,000 IU of vitamin D3) per day. If higher doses of cholecalciferol are required, higher doses of drugs should be used.
During long-term treatment with Aquadetrim Vitamin D3, it is necessary to regularly monitor the level of creatinine in the blood and the level of calcium in the blood serum and urine. If necessary, the dose should be adjusted depending on the concentration of calcium in the blood serum.
Duration and method of application.
Children are prescribed Aquadetrim Vitamin D3 to prevent rickets, starting from the second week of life by the end of 1 year of life. During the second year of life, there may be a need for further use of the drug Aquadetrim Vitamin D3, especially in winter.
For small children, give drops in a teaspoon of water, milk or baby food. If the drops are added to a feeding bottle or plate, it is necessary to ensure that the food is consumed completely, otherwise the entire dose of the drug cannot be guaranteed. Add the drug to food immediately before eating it.
Adults and older children take the drug in a spoonful of liquid.
The duration of treatment depends on the course and severity of the disease and is determined by the doctor individually. Treatment of rickets and osteomalacia caused by vitamin D3 deficiency continues for 1 year.
1 drop contains 500 IU of vitamin D3. To accurately measure the dose of the drug, you need to hold the bottle at an angle of 45 ° during dripping.
When using doses of more than 1000 IU of vitamin D3 per day, as well as with continuous administration of the drug, the level of calcium in the blood serum should be monitored.
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