Description

Arifam (indapamide) tablets with modified release 1.5 mg/10 mg. №30

Ingredients

Active ingredient: Indapamide.
Other ingredients: lactose monohydrate, hypromellose, magnesium stearate, and more.

Dosage

Recommended dosage: 1 tablet daily, preferably in the morning with or without food.
Do not exceed the recommended dose.

Indications

Arifam tablets are indicated for the treatment of hypertension (high blood pressure).

Contraindications

Do not use Arifam tablets if you are allergic to indapamide or any other ingredients in the formulation.
Consult your healthcare provider before use if you have severe renal impairment.

Directions

Swallow the tablet whole with a glass of water. Do not crush or chew the tablet.
Follow the dosage instructions provided by your healthcare provider.

Scientific Evidence

Indapamide, the active ingredient in Arifam tablets, is a thiazide-like diuretic that works by increasing the excretion of sodium and water by the kidneys. This action helps to reduce blood pressure and lower the risk of cardiovascular events. Studies have shown that indapamide is effective in managing hypertension and reducing the incidence of stroke and other cardiovascular complications.

Additional Information

It is important to monitor electrolyte levels regularly while taking Arifam tablets, especially potassium levels.
Inform your healthcare provider about all the medications you are taking before starting Arifam to prevent potential drug interactions.

Pharmacological Effects: Indapamide acts on the distal convoluted tubule of the kidney to promote diuresis and lower blood pressure. It also exhibits vasodilatory effects, further aiding in blood pressure reduction.

Clinical Trials: Clinical trials have demonstrated the efficacy of indapamide in reducing blood pressure and cardiovascular risks. A study published in the Journal of Hypertension showed that indapamide-based therapy significantly reduced the incidence of stroke compared to placebo.