Description

Azaleptol (Clozapine) tablets 0.1 №50

Ingredients

Active ingredient: Clozapine
Other ingredients: lactose monohydrate, maize starch, povidone, magnesium stearate.

Dosage

Dosage: The usual starting dose is 12.5 mg once or twice daily, with gradual increments to reduce the risk of adverse effects. The maintenance dose ranges from 300 mg to 450 mg per day in divided doses.

Indications

Indications: Azaleptol (Clozapine) is indicated for the treatment of severe schizophrenia in patients who have not responded to standard antipsychotic medications.

Contraindications

Contraindications: Do not use Azaleptol (Clozapine) if the patient has a history of agranulocytosis, severe neutropenia, or hypersensitivity to clozapine.

Directions

Directions: Take Azaleptol (Clozapine) tablets orally with or without food as directed by your healthcare provider. Do not suddenly stop taking this medication without consulting your doctor.

Scientific Evidence

Azaleptol (Clozapine) has shown superior efficacy in the treatment of refractory schizophrenia compared to other antipsychotic medications. Studies have demonstrated its effectiveness in reducing positive and negative symptoms of schizophrenia and improving overall quality of life in patients.

Additional Information

It is important to regularly monitor blood counts while on Azaleptol (Clozapine) therapy due to the risk of agranulocytosis. Patients should be educated about the signs of infection and advised to seek immediate medical attention if symptoms such as fever or sore throat occur.

Pharmacological Effects

Clozapine, the active ingredient in Azaleptol, acts as an antagonist at various neurotransmitter receptors in the brain, including dopamine and serotonin receptors. This unique pharmacological profile contributes to its efficacy in treating schizophrenia, especially in cases where other antipsychotic medications have failed.

Clinical Trials and Comparative Effectiveness

Clinical trials have shown that Azaleptol (Clozapine) is more effective in improving symptoms and reducing hospitalizations in patients with treatment-resistant schizophrenia compared to other antipsychotic drugs. Its superior efficacy has made it a valuable option for individuals who do not respond adequately to conventional treatments.

Overall, Azaleptol (Clozapine) tablets 0.1 №50 offer a well-established treatment option for patients with severe schizophrenia, backed by scientific evidence and clinical trials supporting its efficacy in managing this challenging condition.