Description
Carbalex (carbamazepine) retard tablets 300 mg. №100
Ingredients
Each tablet contains 300 mg of carbamazepine.
Mechanism of Action
Carbamazepine works by stabilizing electrical activity in the brain, specifically by blocking voltage-gated sodium channels, which helps in controlling seizures in patients with epilepsy.
Pharmacological Properties
Carbamazepine belongs to the class of anticonvulsant medications. It exerts its therapeutic effects by modulating sodium channels in neural membranes, thereby regulating neuronal excitability.
Indications for Use
Carbalex (carbamazepine) retard tablets are indicated for the treatment of epilepsy and trigeminal neuralgia. They are recommended for patients requiring antiepileptic therapy or relief from trigeminal neuralgia symptoms.
Contraindications
Carbalex should not be used in individuals with a known hypersensitivity to carbamazepine or a history of bone marrow suppression. Patients with a history of hypersensitivity reactions to tricyclic antidepressants may also be at risk of cross-reactivity.
Side Effects
Common side effects of Carbalex may include dizziness, drowsiness, nausea, vomiting, and skin rashes. Serious but rare side effects may include agranulocytosis, aplastic anemia, and hepatic toxicity. Patients should seek immediate medical attention if they experience any signs of these serious side effects.
Usage Instructions
The usual starting dose of Carbalex is 200 mg taken twice daily. Dosage adjustments should be made based on individual response and therapeutic needs. The tablets should be taken orally with or without food, swallowed whole, and not crushed or chewed.
Benefits Compared to Analogues
Carbamazepine, the active ingredient in Carbalex tablets, has a well-established efficacy and safety profile in the management of epilepsy and trigeminal neuralgia. Its long-standing use and proven clinical outcomes make it a preferred choice for many healthcare providers.
Suitable Patient Groups
Carbalex can be used in various patient populations, including adults, children, and the elderly. However, special caution is advised in the elderly population due to the increased risk of adverse effects and drug interactions. Dosage adjustments may be necessary in these cases.
Storage and Shelf Life
Carbalex tablets should be stored at room temperature away from moisture and heat. The shelf life of the product is typically mentioned on the packaging and should be adhered to for optimal efficacy and safety.
Packaging Description
Carbalex (carbamazepine) retard tablets are typically packaged in blister packs or bottles containing a specific number of tablets. The packaging should be inspected for any signs of tampering before use.
Clinical Evidence and Proven Effectiveness
Carbamazepine has been extensively studied in clinical trials, demonstrating its efficacy in reducing seizure frequency and managing trigeminal neuralgia symptoms. Clinical studies have shown that Carbalex is well-tolerated and effective in the long-term treatment of these conditions.
