Description
Cifran (Ciprofloxacin) Coated Tablets 500 mg. №10
Ingredients:
Each tablet contains 500 mg of ciprofloxacin as the active ingredient.
Mechanism of Action:
Ciprofloxacin, the active ingredient in Cifran tablets, is a broad-spectrum antibiotic that works by inhibiting the bacterial DNA gyrase enzyme, thereby preventing DNA supercoiling and replication. This mechanism of action makes ciprofloxacin effective against a wide range of bacteria.
Pharmacological Properties:
Ciprofloxacin exhibits potent bactericidal activity by interfering with the DNA replication process of susceptible bacteria, leading to their eventual death. It has a broad spectrum of activity against both Gram-positive and Gram-negative bacteria.
Indications for Use:
Cifran tablets are indicated for the treatment of various bacterial infections, including urinary tract infections, respiratory tract infections, skin and soft tissue infections, and bone and joint infections.
Contraindications:
Do not use Cifran tablets if you are allergic to ciprofloxacin or any other fluoroquinolones. Avoid use in patients with a history of tendon disorders related to fluoroquinolone use.
Side Effects:
Common side effects of Cifran tablets may include nausea, diarrhea, headache, dizziness, and abdominal pain. Serious side effects such as tendon rupture, peripheral neuropathy, and central nervous system effects may occur rarely.
Usage Instructions:
The usual dosage is one tablet (500 mg) twice a day, or as directed by a healthcare professional. Swallow the tablet whole with a full glass of water. Do not crush or chew the tablet.
Benefits Compared to Analogues:
Cifran tablets offer the advantage of a convenient dosing regimen and a broad spectrum of antibacterial coverage compared to some other antibiotics. The efficacy of ciprofloxacin in treating multidrug-resistant bacterial infections further enhances its clinical utility.
Suitable Patient Groups:
Cifran tablets can be used in adults of all age groups. Caution is advised when prescribing to pediatric patients, pregnant women, and elderly individuals, taking into consideration the potential risks and benefits in these populations.
Storage Conditions and Shelf Life:
- Store Cifran tablets in a cool, dry place away from direct sunlight.
- Keep the tablets in their original packaging to protect them from moisture.
- Check the expiration date on the packaging and do not use expired tablets.
Packaging Description:
Cifran tablets are supplied in blister packs containing 10 coated tablets of 500 mg each. The packaging is designed to maintain the stability and integrity of the tablets throughout their shelf life.
Clinical Evidence and Proven Effectiveness:
Several studies have demonstrated the efficacy of ciprofloxacin in treating various bacterial infections. For example, a study published in the Journal of Antimicrobial Chemotherapy found that ciprofloxacin was highly effective in the treatment of urinary tract infections caused by multidrug-resistant bacteria.
In conclusion, Cifran (ciprofloxacin) coated tablets 500 mg. №10 are a potent antibiotic with a well-established efficacy in treating various bacterial infections. The pharmacological action of ciprofloxacin makes it a valuable option for healthcare providers in managing infections effectively.
Clinical trials and research studies continue to support the use of ciprofloxacin in clinical practice, highlighting its role as a cornerstone antibiotic in the treatment of bacterial infections.
