Description

Cimacef (cefuroxime) 0.75 g. vial intravenous №1

Ingredients

Active ingredient: Cefuroxime. Inactive ingredients may include sodium carbonate, sodium chloride, and sterile water for injection.

Dosage

Dosage: The usual adult dose is 750 mg to 1.5 grams every 8 hours, depending on the severity of the infection. Dosage adjustments may be necessary in patients with renal impairment.

Indications

Indications: Cimacef is indicated for the treatment of infections caused by susceptible strains of bacteria, including lower respiratory tract infections, skin and skin structure infections, and urinary tract infections.

Contraindications

Contraindications: Cimacef is contraindicated in patients with a known allergy to cephalosporins.

Directions

Administration: Cimacef is for intravenous use only. It should be administered over a period of 30 minutes to 1 hour.

Scientific Evidence

Cefuroxime, the active ingredient in Cimacef, is a second-generation cephalosporin antibiotic with broad-spectrum activity against various bacteria. Studies have shown its efficacy in treating a range of infections, including community-acquired pneumonia and skin infections. Research published in the International Journal of Antimicrobial Agents highlighted the effectiveness of cefuroxime in combating multidrug-resistant pathogens.

Additional Information

Cimacef’s pharmacological action involves inhibiting bacterial cell wall synthesis, leading to bacterial cell death. Clinical trials have demonstrated Cimacef’s effectiveness in treating complicated urinary tract infections and intra-abdominal infections. Compared to other cephalosporins, Cimacef exhibits enhanced stability against beta-lactamases, making it a valuable option in the era of increasing antibiotic resistance.

Overall, Cimacef (cefuroxime) 0.75 g. vial intravenous №1 is a potent antibiotic with a well-established efficacy profile supported by scientific evidence and clinical trials. Its broad-spectrum activity and favorable pharmacokinetics make it a valuable choice for healthcare providers in the management of various bacterial infections.