Description

Climen (estradiol valerate, cyproterone acetate) Coated Tablets №21

Ingredients

Active ingredients: Each tablet contains estradiol valerate and cyproterone acetate.

Dosage

Dosage: The usual dose is one tablet daily for 21 days, followed by a 7-day break.

Indications

Indications: Climen is indicated for hormone replacement therapy in postmenopausal women with an intact uterus.

Contraindications

Contraindications: Do not use Climen in cases of hypersensitivity to the active substances, liver disease, or a history of hormone-related cancers.

Directions

Directions: Take one tablet daily with water at the same time each day. Follow the prescribed regimen strictly.

Scientific Evidence

Pharmacological Effects: Estradiol valerate provides estrogen replacement, while cyproterone acetate acts as an anti-androgen, reducing androgen levels. This combination helps alleviate menopausal symptoms and regulate hormone imbalances.

Clinical Trials: Studies have shown that Climen is effective in reducing hot flashes, night sweats, and other menopausal symptoms. Additionally, the anti-androgenic properties of cyproterone acetate make it beneficial in conditions like hirsutism and acne.

Additional Information

Comparative Effectiveness: Climen has been compared to other hormone replacement therapies and has shown similar efficacy in managing menopausal symptoms with the added benefit of anti-androgenic effects.

Safety Profile: It is important to follow the prescribed dosage and regimen to minimize the risk of adverse effects. Consult a healthcare provider before starting Climen to ensure it is suitable for your individual health needs.