Description
Climen (Estradiol Valerate, Cyproterone Acetate) Coated Tablets №21
Ingredients
Active ingredients: Each tablet contains estradiol valerate and cyproterone acetate.
Mechanism of Action
Pharmacological Properties: Estradiol valerate provides estrogen replacement, while cyproterone acetate acts as an anti-androgen, reducing androgen levels. This combination helps alleviate menopausal symptoms and regulate hormone imbalances.
Indications for Use
Indications: Climen is indicated for hormone replacement therapy in postmenopausal women with an intact uterus.
Contraindications
Contraindications: Do not use Climen in cases of hypersensitivity to the active substances, liver disease, or a history of hormone-related cancers.
Side Effects
Side Effects: Common side effects may include nausea, breast tenderness, headache, and breakthrough bleeding. Rare but serious side effects may include thromboembolism and liver problems.
Usage Instructions
Dosage: The usual dose is one tablet daily for 21 days, followed by a 7-day break. Take one tablet daily with water at the same time each day. Follow the prescribed regimen strictly.
Benefits Compared to Analogues
Comparative Effectiveness: Climen has been compared to other hormone replacement therapies and has shown similar efficacy in managing menopausal symptoms with the added benefit of anti-androgenic effects.
Suitable Patient Groups
Suitable Patients: Climen is suitable for postmenopausal women with an intact uterus. It is not recommended for use in children, men, or individuals with certain medical conditions without medical supervision.
Storage and Shelf Life
Storage: Store Climen in a cool, dry place away from direct sunlight. Keep out of reach of children.
Shelf Life: Check the expiration date on the packaging. Do not use Climen after the expiry date.
Packaging Description
Packaging: Climen is available in blister packs containing 21 coated tablets. Each pack is labeled with the product name, dosage information, and active ingredients.
Clinical Evidence and Proven Effectiveness
Scientific Evidence: Clinical studies have shown that Climen is effective in reducing hot flashes, night sweats, and other menopausal symptoms. Additionally, the anti-androgenic properties of cyproterone acetate make it beneficial in conditions like hirsutism and acne.
Safety Profile: It is important to follow the prescribed dosage and regimen to minimize the risk of adverse effects. Consult a healthcare provider before starting Climen to ensure it is suitable for your individual health needs.
