Description

Clodifen (diclofenac) solution for injections 25 mg/ml. 3 ml. №5

Ingredients

Active ingredient: diclofenac sodium. Other ingredients: mannitol, propylene glycol, sodium hydroxide, and water for injections.

Dosage

Recommended dosage: The usual dose is 75 mg to 150 mg daily in divided doses. The maximum daily dose should not exceed 150 mg.

Indications

Clodifen solution for injections is indicated for the treatment of pain and inflammation associated with various conditions such as rheumatoid arthritis, osteoarthritis, ankylosing spondylitis, and acute gout.

Contraindications

Do not use Clodifen solution for injections if you have a history of allergic reactions to diclofenac or other NSAIDs, active peptic ulcer, severe heart failure, or during the third trimester of pregnancy.

Directions

Administer Clodifen solution for injections via intramuscular or intravenous route. The injection should be given slowly over 3 to 5 minutes.

Scientific Evidence

Diclofenac is a nonsteroidal anti-inflammatory drug (NSAID) that works by inhibiting the enzyme cyclooxygenase, thereby reducing the production of prostaglandins which are mediators of pain and inflammation. Several studies have demonstrated the efficacy of diclofenac in managing various painful conditions.

Additional Information

Clodifen solution for injections provides a rapid onset of action, making it suitable for the management of acute pain. It is important to monitor for potential side effects such as gastrointestinal ulcers, renal impairment, and cardiovascular risks when using this medication.

Research has shown that diclofenac is comparable in effectiveness to other NSAIDs such as ibuprofen and naproxen, with similar rates of pain relief and adverse effects. However, individual responses to different NSAIDs may vary, and the choice of medication should be based on the patient’s specific needs and medical history.