Description

Closart (losartan) Coated Tablets 100 mg. №100

Ingredients

Active ingredient: Losartan potassium 100 mg.
Other ingredients: Microcrystalline cellulose, lactose monohydrate, croscarmellose sodium, magnesium stearate, hypromellose, macrogol, titanium dioxide (E171).

Dosage

Adults: The usual starting dose is 50 mg once daily. The dosage can be increased to a maximum of 100 mg once daily. Consult a healthcare provider for personalized dosing.

Indications

Closart (losartan) tablets are indicated for the treatment of hypertension and to reduce the risk of stroke in patients with hypertension and left ventricular hypertrophy.

Contraindications

Do not use Closart tablets if you:

• Are allergic to losartan or any other ingredients in the product.
• Are pregnant, as it can cause harm to the unborn baby.
• Have severe liver disease.

Directions

Take Closart tablets exactly as prescribed by your healthcare provider. Swallow the tablet whole with a glass of water. It can be taken with or without food.

Scientific Evidence

Losartan, the active ingredient in Closart tablets, is an angiotensin II receptor blocker that works by relaxing blood vessels. Studies have shown that losartan is effective in lowering blood pressure and reducing the risk of cardiovascular events. Research published in the Journal of Hypertension demonstrated the efficacy of losartan in improving cardiovascular outcomes in hypertensive patients.

Additional Information

It is important to regularly monitor blood pressure levels while taking Closart tablets. Inform your healthcare provider about any other medications or supplements you are taking to avoid potential drug interactions. In case of any adverse reactions or concerns, seek medical help immediately.

Pharmacological Effects: Losartan blocks the action of angiotensin II, a substance in the body that causes blood vessels to constrict. By blocking this action, losartan helps blood vessels relax and widen, lowering blood pressure.

Clinical Trials: Clinical trials have shown that losartan is as effective as other antihypertensive medications in reducing blood pressure. A study published in the New England Journal of Medicine compared the efficacy of losartan with atenolol and found similar cardiovascular outcomes in patients with hypertension.