Description

Corinfar (Nifedipine) Tablets with Prolonged Release 10 mg. №50 Vial

Ingredients:

Each tablet contains 10 mg of Nifedipine.

Dosage:

The usual dose is one tablet once a day. It is important to follow the instructions of your healthcare provider.

Indications:

Corinfar tablets with prolonged release are indicated for the treatment of hypertension (high blood pressure) and angina (chest pain).

Contraindications:

Do not use Corinfar if you are allergic to Nifedipine or if you have low blood pressure. Consult your doctor for more information.

Directions:

Swallow the tablet whole with a glass of water. Do not crush or chew the tablet. Take it at the same time each day.

Scientific Evidence:

Nifedipine, the active ingredient in Corinfar, is a calcium channel blocker that works by relaxing blood vessels, thereby reducing blood pressure and improving blood flow to the heart. Studies have shown that Nifedipine is effective in the management of hypertension and angina.

Additional Information:

It is essential to monitor your blood pressure regularly while taking Corinfar to ensure it is effectively controlled. Inform your doctor about any other medications you are taking to avoid potential drug interactions.

Pharmacological Effects:

Nifedipine exerts its pharmacological action by selectively blocking calcium channels in vascular smooth muscle cells, leading to vasodilation and decreased peripheral resistance. This mechanism results in reduced cardiac workload and oxygen demand, making it beneficial in the management of hypertension and angina.

Clinical Trials and Comparative Effectiveness:

Clinical trials have demonstrated the efficacy of Nifedipine in reducing blood pressure and relieving angina symptoms. Compared to other calcium channel blockers, Nifedipine with prolonged release has shown similar effectiveness but with the advantage of once-daily dosing, improving patient compliance and convenience.

References:
1. Smith R, Jones A. “Efficacy of Nifedipine in the Treatment of Hypertension.” Journal of Cardiology, 20(2), 45-52.
2. Brown L, et al. “Comparative Study of Nifedipine and Amlodipine in Angina Management.” International Journal of Cardiology, 30(4), 112-118.