Description
Coriol (carvedilol) tablets 6.25 mg. №28
Ingredients
Active ingredient: Carvedilol 6.25 mg per tablet.
Mechanism of Action
Carvedilol, a non-selective beta-blocker with alpha-blocking properties, works by blocking beta receptors in the heart and blood vessels, leading to a decrease in heart rate and blood pressure. It also dilates blood vessels, improving blood flow and reducing the workload on the heart.
Pharmacological Properties
Carvedilol has been extensively studied in clinical trials for its efficacy in managing hypertension and heart failure. It reduces cardiovascular mortality and hospitalizations in heart failure patients, improves left ventricular function, and effectively decreases blood pressure.
Indications for Use
Coriol tablets are indicated for the treatment of hypertension, heart failure, and left ventricular dysfunction following myocardial infarction.
Contraindications
Do not use Coriol tablets if you have bronchial asthma, certain heart conditions, severe liver impairment, or are allergic to carvedilol.
Side Effects
Common side effects of carvedilol may include dizziness, fatigue, low blood pressure, and slow heart rate. Consult your healthcare provider for a full list of possible side effects.
Usage Instructions
Dosage: The usual starting dose is one 6.25 mg tablet twice daily. Dosage may be increased gradually.
Directions: Take Coriol tablets by mouth with food. Do not crush or chew the tablets. Follow the dosage instructions provided by your healthcare provider.
Benefits Compared to Analogues
Coriol tablets offer the benefit of dual beta and alpha-blocking properties, providing comprehensive management of hypertension and heart failure compared to single mechanism drugs.
Suitable Patient Groups
Coriol tablets are suitable for adult patients with hypertension, heart failure, or left ventricular dysfunction. Dosage adjustments may be necessary for elderly patients or those with specific medical conditions.
Storage and Shelf Life
Coriol tablets should be stored at room temperature away from moisture and heat. Keep out of reach of children. Check the expiration date on the packaging and do not use if expired.
Packaging Description
Coriol tablets are available in a pack of 28 tablets, each containing 6.25 mg of carvedilol.
Clinical Evidence and Proven Effectiveness
Carvedilol has shown significant efficacy in reducing the risk of cardiovascular events and improving outcomes in patients with heart failure and hypertension. Clinical studies have demonstrated its ability to lower mortality rates, reduce hospitalizations, and enhance overall cardiovascular function.
