Description
Depakin Chrono (sodium valproate) Coated Tablets with Prolonged Release 300 mg. №100
Ingredients:
Each coated tablet contains 300 mg of sodium valproate.
Mechanism of Action:
Sodium valproate works by increasing the levels of gamma-aminobutyric acid (GABA) in the brain, a neurotransmitter that helps calm excessive electrical nerve activity. This mechanism aids in controlling seizures and stabilizing mood in bipolar disorder.
Pharmacological Properties:
Depakin Chrono, with sodium valproate as the active ingredient, exhibits anticonvulsant and mood-stabilizing properties. It modulates GABA levels to regulate neuronal excitability, thereby reducing seizure activity and mood fluctuations.
Indications for Use:
Depakin Chrono is indicated for the treatment of epilepsy and bipolar disorder. It is effective in seizure management and mood stabilization.
Contraindications:
Avoid Depakin Chrono if allergic to sodium valproate or any tablet components. Contraindicated in individuals with liver disease or urea cycle disorders due to potential adverse effects.
Side Effects:
Common side effects may include nausea, dizziness, drowsiness, and weight gain. Serious side effects such as liver toxicity or pancreatitis may occur in rare cases.
Usage Instructions:
The typical initial dose is 600 mg daily, split into two doses. Dosage adjustments should be made based on individual response. Swallow tablets whole with water, preferably with food to minimize gastrointestinal discomfort.
Benefits Compared to Analogues:
Depakin Chrono offers comparable efficacy to other antiepileptic medications with a favorable side effect profile. Its prolonged-release formulation allows for convenient once or twice-daily dosing.
Suitable Patient Groups:
Depakin Chrono is suitable for both pediatric and elderly patients under appropriate medical supervision. Dosing adjustments may be necessary based on age and health status.
Storage and Shelf Life:
Store Depakin Chrono in a cool, dry place away from direct sunlight. Check the packaging for the expiration date and adhere to proper storage conditions to maintain product integrity.
Packaging Description:
Depakin Chrono is available in blister packs containing 100 coated tablets of 300 mg each. The packaging is designed to ensure product stability and ease of use.
Clinical Evidence and Proven Effectiveness:
Depakin Chrono, containing sodium valproate, has demonstrated efficacy in managing epilepsy and bipolar disorder. Studies in reputable journals have shown its effectiveness in reducing seizure frequency and severity, as well as stabilizing mood swings.
