Description
Diaformin (Metformin) Tablets 500 mg. №60
Ingredients:
Each tablet contains 500 mg of metformin hydrochloride.
Mechanism of Action:
Metformin works by decreasing glucose production in the liver and improving insulin sensitivity in the body’s tissues, leading to lower blood sugar levels and better diabetes control. It also has positive effects on lipid profiles by reducing LDL cholesterol and triglycerides.
Pharmacological Properties:
Metformin is a biguanide that reduces hepatic glucose production, increases insulin sensitivity, and improves peripheral glucose uptake. It does not stimulate insulin secretion and does not cause hypoglycemia.
Indications:
Diaformin tablets are indicated for the management of type 2 diabetes mellitus. They help control blood sugar levels and may prevent complications associated with diabetes.
Contraindications:
Avoid using Diaformin if you have severe kidney disease or metabolic acidosis. Consult a healthcare provider before initiating treatment with this medication.
Side Effects:
Possible side effects of Diaformin include gastrointestinal disturbances such as nausea and diarrhea. These effects often diminish with continued use.
Usage Instructions:
The usual starting dose is one tablet of 500 mg once daily with the evening meal. Dosage adjustments may be made based on blood glucose levels. Swallow the tablets whole with a glass of water; do not crush or chew them.
Benefits Compared to Analogues:
Metformin has been extensively studied and consistently shown to effectively reduce blood glucose levels and improve overall glycemic control compared to other antidiabetic medications. It has also been associated with a lower risk of cardiovascular events than some oral antidiabetic drugs.
Suitable Patient Groups:
Diaformin can be used in various patient populations, including adults, elderly individuals, and adolescents with type 2 diabetes. However, dosage adjustments may be necessary based on individual health conditions and renal function.
Storage Conditions and Shelf Life:
Store Diaformin tablets in a cool, dry place away from moisture and heat. Check the expiration date on the packaging and do not use the tablets beyond this date.
Packaging Description:
Diaformin tablets are available in a pack of 60 tablets, with each tablet containing 500 mg of metformin hydrochloride. The packaging is designed to maintain the integrity and quality of the tablets.
Clinical Evidence and Proven Effectiveness:
Numerous studies have demonstrated the efficacy of metformin in managing type 2 diabetes. Research published in the Journal of Clinical Endocrinology & Metabolism has shown that metformin significantly reduces hemoglobin A1c levels, indicating improved long-term glucose control. Clinical trials have consistently highlighted the benefits of metformin in reducing cardiovascular risk compared to other antidiabetic agents.
