Description

Diamax (diacerein) capsules 50 mg. №30

Ingredients:

Each capsule contains 50 mg of diacerein as the active ingredient.

Dosage:

The recommended dosage is one 50 mg capsule taken orally once daily with a meal.

Indications:

Diamax capsules are indicated for the treatment of osteoarthritis to reduce pain and improve joint function.

Contraindications:

Do not use Diamax capsules if you are allergic to diacerein or have a history of inflammatory bowel disease.

Directions:

Swallow the capsule whole with a full glass of water. Do not crush or chew the capsule.

Scientific Evidence:

Diacerein, the active ingredient in Diamax capsules, has been extensively studied for its efficacy in the treatment of osteoarthritis. Research has shown that diacerein helps to reduce pain, improve joint function, and slow down the progression of the disease by inhibiting interleukin-1 beta, a key inflammatory mediator in osteoarthritis.

Additional Information:

Diamax capsules should be stored at room temperature away from moisture and heat. Keep out of reach of children. Consult your healthcare provider before starting Diamax capsules, especially if you are pregnant, nursing, or have any underlying medical conditions.

Pharmacological Effects:

Diacerein exerts its pharmacological action by inhibiting the production of interleukin-1 beta, a cytokine involved in the inflammatory process of osteoarthritis. By reducing the levels of this pro-inflammatory mediator, diacerein helps to alleviate pain, swelling, and stiffness in the joints, thereby improving the overall quality of life for patients with osteoarthritis.

Clinical Trials and Comparative Effectiveness:

In a randomized controlled trial published in the Journal of Rheumatology, diacerein was found to be as effective as nonsteroidal anti-inflammatory drugs (NSAIDs) in relieving pain and improving joint function in patients with knee osteoarthritis. Furthermore, diacerein was associated with a lower risk of gastrointestinal side effects compared to NSAIDs, making it a valuable alternative for patients who are intolerant to traditional pain medications.