Description
Dicloberl-100 (Diclofenac Sodium) Suppositories 100 mg. №10
Ingredients:
Active ingredient: Diclofenac sodium 100 mg per suppository.
Dosage:
Adults: The usual dose is one suppository inserted into the rectum once daily.
Indications:
Dicloberl-100 suppositories are indicated for the relief of pain and inflammation in conditions such as rheumatoid arthritis, osteoarthritis, and ankylosing spondylitis.
Contraindications:
Do not use Dicloberl-100 suppositories if you have a history of allergic reactions to diclofenac or other NSAIDs, or if you have active peptic ulcers.
Directions:
For rectal use only. Wash hands before and after use. Lie on your side and insert the suppository into the rectum. Follow the instructions provided by your healthcare provider.
Scientific Evidence:
Diclofenac, the active ingredient in Dicloberl-100 suppositories, is a potent nonsteroidal anti-inflammatory drug (NSAID) that works by inhibiting the enzyme cyclooxygenase, thereby reducing the production of prostaglandins involved in inflammation and pain. Studies have shown diclofenac to be effective in managing various painful conditions, with rectal administration providing a rapid onset of action.
Additional Information:
Dicloberl-100 suppositories offer a convenient and effective way to deliver diclofenac for individuals who may have difficulty swallowing tablets or capsules. It is important to follow the recommended dosage and precautions to minimize the risk of adverse effects. Consult your healthcare provider for personalized advice on the use of this medication.
Pharmacological Properties:
Diclofenac, a phenylacetic acid derivative, exerts its pharmacological effects by inhibiting the enzyme cyclooxygenase, leading to decreased prostaglandin synthesis. This results in anti-inflammatory, analgesic, and antipyretic actions.
Side Effects:
- Gastrointestinal disturbances
- Renal impairment
- Cardiovascular risks
- Skin reactions
Benefits Compared to Analogues:
Dicloberl-100 suppositories offer a targeted approach to pain relief with rapid onset of action due to rectal administration. This route of administration may be advantageous for patients with gastrointestinal sensitivities or difficulties in swallowing oral medications.
Suitable Patient Groups:
While Dicloberl-100 is primarily indicated for adults, it can also be used in specific pediatric cases under the guidance of a healthcare provider. Caution is advised in elderly patients and those with renal or hepatic impairment.
Storage Conditions and Shelf Life:
Store Dicloberl-100 suppositories in a cool, dry place away from direct sunlight. Ensure proper sealing of the packaging to prevent moisture ingress. Check the expiration date on the packaging and do not use beyond the stated shelf life.
Packaging Description:
Dicloberl-100 suppositories are individually packed in foil wrappers to maintain product integrity and ensure sterility. The outer packaging provides essential information such as dosage instructions, indications, and contraindications for user reference.
