Description

Diclofenak (diclofenac) Coated Tablets 0.025 g. №30

Ingredients:

Each coated tablet contains 0.025 g of diclofenac sodium as the active ingredient.

Dosage:

The usual dose for adults is 50 mg to 150 mg per day, divided into 2 or 3 doses. It is important to follow the prescribed dosage by a healthcare professional.

Indications:

Diclofenak coated tablets are indicated for the relief of pain and inflammation in conditions such as arthritis, ankylosing spondylitis, and acute gout. It is also used for the management of dysmenorrhea.

Contraindications:

Do not use diclofenac if you have a history of allergic reactions to NSAIDs, peptic ulcer disease, or renal impairment. It is contraindicated in the third trimester of pregnancy.

Directions:

Swallow the tablets whole with a full glass of water. Do not crush or chew the tablets. Take with food to reduce the risk of gastrointestinal side effects.

Scientific Evidence:

Diclofenac, the active ingredient in diclofenak tablets, is a nonsteroidal anti-inflammatory drug (NSAID) that works by inhibiting the enzyme cyclooxygenase (COX), thereby reducing the production of prostaglandins involved in inflammation, pain, and fever. Studies have shown diclofenac to be effective in managing various painful conditions, including osteoarthritis and rheumatoid arthritis.

Additional Information:

Diclofenac has been extensively studied in clinical trials, demonstrating its efficacy and safety profile. It is important to be aware of potential side effects such as gastrointestinal ulcers, cardiovascular risks, and renal toxicity. Patients should be monitored closely while on diclofenac therapy.

Pharmacologically, diclofenac exhibits analgesic, anti-inflammatory, and antipyretic properties by inhibiting the synthesis of prostaglandins. This action helps alleviate pain and reduce inflammation at the site of injury or inflammation. Additionally, diclofenac has been shown to have a rapid onset of action, providing quick relief to patients.

Comparative studies have suggested that diclofenac is as effective as other NSAIDs in managing pain and inflammation. However, its unique pharmacokinetic profile may offer advantages in certain patient populations. Consult with a healthcare provider to determine the most suitable treatment option based on individual needs and medical history.