Description

Diclofenak (Diclofenac) Gel 1% 50 g

Ingredients:

Diclofenac Sodium, Carbomer, Isopropyl Alcohol, Propylene Glycol, Purified Water.

Dosage:

Apply a thin layer of Diclofenak gel to the affected area 3-4 times daily and gently rub in. Do not cover the treated area with bandages or dressings.

Indications:

Diclofenak gel is indicated for the relief of pain and inflammation associated with osteoarthritis, rheumatoid arthritis, and ankylosing spondylitis.

Contraindications:

Do not use Diclofenak gel if you are allergic to diclofenac or any other ingredients in the gel. Avoid use on open wounds, mucous membranes, or eyes.

Directions:

Clean and dry the affected area before applying the gel. Use the provided dosing card to measure the correct dose. Wash your hands after applying the gel to avoid accidental contact with eyes or mucous membranes.

Scientific Evidence:

Studies have shown that topical diclofenac formulations, such as Diclofenak gel, provide effective pain relief with lower systemic exposure compared to oral formulations. Research published in the Journal of Pain Research demonstrated the efficacy of diclofenac gel in reducing pain and improving function in patients with knee osteoarthritis.

Additional Information:

It is important to follow the recommended dosage and avoid applying Diclofenak gel to large areas of skin or for prolonged periods without medical supervision. If you experience any skin irritation or adverse reactions, discontinue use and consult a healthcare professional.

Pharmacological Effects: Diclofenac, the active ingredient in Diclofenak gel, inhibits the enzyme cyclooxygenase, thereby reducing the production of prostaglandins involved in the inflammatory process. This action helps alleviate pain and swelling at the site of application.

Clinical Trials: Clinical trials have demonstrated the efficacy of diclofenac gel in providing symptomatic relief in various musculoskeletal conditions. A study published in the Journal of Clinical Rheumatology showed that diclofenac gel was well-tolerated and effective in reducing pain intensity in patients with osteoarthritis of the knee.