Description

Digoxin (digoxin) Tablets 0.25 mg. №50

Ingredients

Active ingredient: Digoxin 0.25 mg per tablet.

Dosage

Dosage: The usual maintenance dose is 0.125-0.25 mg once daily. Dosage may vary based on individual patient needs and response.

Indications

Indications: Digoxin is indicated for the treatment of heart failure and atrial fibrillation.

Contraindications

Contraindications: Do not use Digoxin in patients with ventricular fibrillation. Use with caution in patients with certain heart conditions.

Directions

Directions: Take Digoxin exactly as prescribed by your healthcare provider. Do not exceed the recommended dose.

Pharmacological Effects

Digoxin, a cardiac glycoside, works by inhibiting the sodium-potassium ATPase pump, leading to increased intracellular calcium levels. This results in enhanced myocardial contractility and improved cardiac output in heart failure.

Additional Information

It is important to monitor serum digoxin levels regularly to ensure therapeutic levels are maintained. Patients should be educated on the signs of digoxin toxicity, such as nausea, vomiting, and visual disturbances. In case of overdose, seek immediate medical attention.

Clinical Trials and Comparative Effectiveness

Clinical trials have demonstrated the efficacy of Digoxin in improving symptoms and reducing hospitalizations in patients with heart failure when used in conjunction with standard therapies. Comparative studies have shown Digoxin to be equally effective or superior to other heart failure medications in certain patient populations.