Description

Dimedrol (Diphenhydramine) Tablets 50 mg. №10

Composition

Active Ingredient: Each tablet contains Diphenhydramine 50 mg.

Mechanism of Action

Diphenhydramine works by blocking the action of histamine, a key mediator in allergic reactions. It antagonizes the H1 receptor, thereby preventing histamine-induced symptoms.

Pharmacological Properties

Diphenhydramine exhibits antihistaminic effects by inhibiting histamine binding. It also possesses sedative properties due to its ability to cross the blood-brain barrier and act on the central nervous system.

Indications for Use

Dimedrol tablets are indicated for the symptomatic relief of allergies, hay fever, and common cold symptoms, including sneezing, rhinorrhea, and pruritus of the nasal mucosa or throat.

Contraindications

Avoid using Dimedrol tablets if you have a known hypersensitivity to diphenhydramine or are currently on monoamine oxidase inhibitors (MAOIs) due to the risk of drug interactions.

Side Effects

Common side effects of Diphenhydramine may include drowsiness, dry mouth, blurred vision, and urinary retention. In rare cases, it can lead to paradoxical excitation or allergic reactions.

Usage Instructions

Adults: Take 1 tablet orally every 4 to 6 hours as needed, with a maximum of 6 tablets in 24 hours. Children: Consult a healthcare provider for appropriate dosing based on age and weight.

Benefits Compared to Analogues

Dimedrol offers rapid relief from allergic symptoms with a proven safety profile. Its dual antihistaminic and sedative effects make it a versatile option for managing various allergic conditions.

Suitable Patient Groups

Dimedrol is suitable for use in both adult and pediatric populations, with dosing adjustments based on age and individual response. Caution is advised in elderly patients due to the potential for increased sedation.

Storage and Shelf Life

Store Dimedrol tablets in a cool, dry place away from direct sunlight. Check the expiration date on the packaging and do not use the product beyond the stated shelf life.

Packaging Description

Dimedrol tablets are typically packaged in blister packs to ensure individual tablet integrity. Each pack contains 10 tablets, with clear labeling of the active ingredient and dosage strength.

Clinical Evidence and Proven Effectiveness

Diphenhydramine has been extensively studied for its efficacy in managing allergic symptoms. Clinical trials have demonstrated its ability to alleviate itching, sneezing, and nasal congestion effectively. Notably, research published in the Journal of Allergy and Clinical Immunology highlights the antihistaminic properties of diphenhydramine in mitigating allergic manifestations.