Description
Docetaxel Amaxa (docetaxel) Concentrate for Infusions 20 mg/ml, 8 ml (160 mg) №1
Composition
Active Ingredient: Docetaxel. Inactive ingredients may include polysorbate 80, ethanol, and citric acid.
Mechanism of Action
Docetaxel works by inhibiting microtubule disassembly, leading to cell cycle arrest and apoptosis in cancer cells.
Pharmacological Properties
Its mechanism of action results in the slowing down of cancer growth and spread, making it an effective treatment option.
Indications for Use
Docetaxel Amaxa is indicated for the treatment of various cancers, including breast cancer, non-small cell lung cancer, and prostate cancer.
Contraindications
Docetaxel Amaxa is contraindicated in patients with a history of severe hypersensitivity reactions to docetaxel or polysorbate 80.
Side Effects
Common side effects may include neutropenia, peripheral neuropathy, and fluid retention.
Usage Instructions
Docetaxel Amaxa is administered intravenously by a healthcare professional experienced in cytotoxic chemotherapy. Dosage is determined based on the patient’s body surface area and treatment protocol.
Benefits Compared to Analogues
Docetaxel has demonstrated superior effectiveness compared to paclitaxel in certain cancers, with higher response rates and longer progression-free survival.
Suitable Patient Groups
Docetaxel Amaxa can be used in various patient groups including adults, elderly, and pediatric patients under appropriate medical supervision.
Storage and Shelf Life
Store Docetaxel Amaxa as per instructions provided, away from light and moisture. Check the expiration date before use.
Packaging Description
Docetaxel Amaxa is available in a 8 ml concentrate for infusion, packaged as a single vial.
Clinical Evidence and Proven Effectiveness
Several clinical trials have demonstrated the efficacy of docetaxel in treating various cancers. For example, a study in the Journal of Clinical Oncology showed improved overall survival in metastatic breast cancer patients with docetaxel-based chemotherapy.
