Description

Docetaxel Amaxa (docetaxel) concentrate for infusions 20 mg/ml. 8 ml. (160 mg.) №1

Ingredients

Active ingredient: Docetaxel. Inactive ingredients may include polysorbate 80, ethanol, and citric acid.

Dosage

Dosage: The recommended dose of Docetaxel Amaxa for infusion is determined by the patient’s body surface area and the specific protocol used for treatment.

Indications

Indications: Docetaxel Amaxa is indicated for the treatment of various types of cancers, including breast cancer, non-small cell lung cancer, and prostate cancer.

Contraindications

Contraindications: Docetaxel Amaxa is contraindicated in patients with a history of severe hypersensitivity reactions to docetaxel or polysorbate 80.

Directions

Administration: Docetaxel Amaxa is administered intravenously by a healthcare professional experienced in the use of cytotoxic chemotherapy.

Scientific Evidence

Efficacy: Several clinical trials have demonstrated the efficacy of docetaxel in the treatment of various cancers. A study published in the Journal of Clinical Oncology showed that docetaxel-based chemotherapy significantly improved overall survival in patients with metastatic breast cancer.

Additional Information

Pharmacological Effects: Docetaxel works by inhibiting microtubule disassembly, leading to cell cycle arrest and apoptosis in cancer cells. This mechanism makes it effective in slowing down the growth and spread of cancer.

Comparative Effectiveness: Docetaxel has been shown to be more effective than paclitaxel in certain types of cancer. A study published in the European Journal of Cancer compared the two drugs in the treatment of non-small cell lung cancer and found that docetaxel had a higher response rate and longer progression-free survival.

In conclusion, Docetaxel Amaxa is a potent chemotherapy drug with well-established efficacy in the treatment of various cancers. Its pharmacological effects on microtubule stabilization and cell cycle arrest have been supported by scientific evidence from clinical trials. When compared to similar drugs, docetaxel has shown superior effectiveness in certain cancer types, making it a valuable option in oncology treatment regimens.