Description
Dorzoptik Combi (Dorzolamide/Timolol) Eye Drops Solution 20 mg/ml + 5 mg/ml – 5 ml Bottle Dropper №1
Ingredients
Active ingredients: Dorzolamide 20 mg/ml, Timolol 5 mg/ml.
Mechanism of Action
Pharmacological Properties: Dorzoptik Combi works by decreasing the production of aqueous humor in the eye and increasing its outflow, thereby reducing intraocular pressure. Timolol, a beta-blocker, further lowers intraocular pressure by decreasing the production of aqueous humor.
Indications for Use
Indications: Dorzoptik Combi is indicated for the reduction of intraocular pressure in patients with open-angle glaucoma or ocular hypertension.
Contraindications
Contraindications: Do not use Dorzoptik Combi in patients with bronchial asthma, severe chronic obstructive pulmonary disease, sinus bradycardia, second or third-degree atrioventricular block, or overt heart failure.
Side Effects
Side Effects: Common side effects may include ocular discomfort, blurred vision, and eye irritation. Contact your healthcare provider if you experience any persistent or severe side effects.
Usage Instructions
Dosage: The usual dose is one drop of Dorzoptik Combi in the affected eye(s) twice daily. Do not touch the dropper tip to any surface to avoid contamination.
Benefits Compared to Analogues
Dorzoptik Combi combines dorzolamide and timolol to provide additive ocular hypotensive effects, offering enhanced intraocular pressure reduction compared to monotherapy with either component alone.
Suitable Patient Groups
This medication is suitable for adult patients with open-angle glaucoma or ocular hypertension. Use in children, pregnant women, or elderly patients should be determined by a healthcare provider based on individual circumstances.
Storage and Shelf Life
Store Dorzoptik Combi at room temperature away from light and moisture. Do not freeze. Discard any unused medication after the expiration date printed on the bottle.
Packaging Description
Dorzoptik Combi is supplied in a 5 ml bottle with a dropper for easy administration. Each bottle is labeled with the name of the product, active ingredients, concentration, and volume.
Clinical Evidence and Proven Effectiveness
Clinical studies have shown that Dorzoptik Combi effectively lowers intraocular pressure in patients with glaucoma or ocular hypertension. Research by Xiong et al. (2018) demonstrated a significant reduction in intraocular pressure with the combination of dorzolamide and timolol compared to dorzolamide alone.
