Description

Dorzotimol (dorzolamide and timolol) Eye Drops Solution 5 ml. Vial №1

Ingredients

Dorzotimol eye drops contain a combination of dorzolamide and timolol as active ingredients. These components work together to lower intraocular pressure in the eye.

Dosage

The usual dose is one drop in the affected eye(s) twice a day. It is important to follow the prescribed dosage and administration instructions provided by your healthcare provider.

Indications

Dorzotimol eye drops are indicated for the reduction of elevated intraocular pressure in patients with open-angle glaucoma or ocular hypertension.

Contraindications

Do not use Dorzotimol eye drops if you are allergic to dorzolamide, timolol, or any other ingredients in the product. It is important to inform your healthcare provider about any allergies before starting this medication.

Directions

Before using the eye drops, wash your hands. Tilt your head back, pull down the lower eyelid, and instill the prescribed number of drops. Close your eyes for a few minutes without blinking.

Scientific Evidence

Studies have shown that the combination of dorzolamide and timolol in Dorzotimol eye drops effectively reduces intraocular pressure in patients with glaucoma. Research published in the Journal of Ophthalmology demonstrated a significant decrease in intraocular pressure with the use of dorzolamide and timolol combination therapy.

Additional Information

It is essential to keep the eye drop vial tightly closed when not in use and store it at room temperature away from moisture and heat. If you experience any eye irritation or adverse effects while using Dorzotimol eye drops, contact your healthcare provider promptly.

Pharmacologically, dorzolamide inhibits carbonic anhydrase in the ciliary processes of the eye, reducing aqueous humor production. Timolol, a non-selective beta-adrenergic receptor blocker, decreases aqueous humor formation by reducing the production of cyclic adenosine monophosphate (cAMP). This dual mechanism of action results in decreased intraocular pressure.

Clinical trials have shown that the combination of dorzolamide and timolol is more effective in lowering intraocular pressure compared to either component used alone. A study published in the British Journal of Ophthalmology demonstrated superior efficacy of the dorzolamide-timolol combination over timolol alone in patients with glaucoma.