Description

Efferalgan (Paracetamol) Oral Solution 3% 90 ml Vial

Ingredients

Active ingredient: Paracetamol 3% w/v. Other ingredients: sucrose, sodium benzoate, sodium citrate, citric acid, purified water.

Dosage

Dosage: Adults and children over 12 years: 10-20 ml every 4-6 hours as needed. Maximum 80 ml in 24 hours. Children 6-12 years: 5-10 ml every 4-6 hours. Maximum 40 ml in 24 hours.

Indications

Indications: Relief of mild to moderate pain such as headache, toothache, musculoskeletal conditions, fever.

Contraindications

Contraindications: Hypersensitivity to paracetamol. Severe liver impairment. Alcoholism. Pregnancy (unless advised by a healthcare professional).

Directions

Directions: Shake well before use. Use the measuring cup provided. Can be taken with or without food. Do not exceed the recommended dose.

Scientific Evidence

Paracetamol is a well-established analgesic and antipyretic medication with a proven safety profile. Studies have shown its effectiveness in managing pain and reducing fever. Research published in the British Journal of Clinical Pharmacology highlights the efficacy of paracetamol in various pain conditions, making it a widely used over-the-counter medication.

Additional Information

In clinical trials, paracetamol has been compared to other pain relievers like ibuprofen, showing similar effectiveness in pain reduction with fewer gastrointestinal side effects. It is considered a first-line treatment for many common ailments due to its safety and tolerability profile.

Paracetamol works by inhibiting the production of prostaglandins in the brain that cause pain and fever. It is rapidly absorbed in the gastrointestinal tract and has a quick onset of action, making it a popular choice for quick relief.

Studies have also suggested that paracetamol may have additional mechanisms of action beyond its known effects on pain and fever, including potential anti-inflammatory properties. Further research is ongoing to explore these potential benefits.