Description
Efmerin (Ceftriaxone) Powder for Solution for Injections 1g. №1 Vial
Ingredients
Active Ingredient: Ceftriaxone. Inactive ingredients may include diluents such as disodium calcium edetate, sodium hydroxide, and water for injections.
Mechanism of Action
Ceftriaxone exerts its bactericidal effects by inhibiting bacterial cell wall synthesis, leading to cell death. It is effective against a wide range of gram-positive and gram-negative bacteria.
Pharmacological Properties
- Ceftriaxone is a third-generation cephalosporin antibiotic.
- It has a broad spectrum of activity against various bacteria.
- It is highly stable and can be administered intravenously or intramuscularly.
Indications for Use
Efmerin is indicated for the treatment of bacterial infections, including:
- Respiratory tract infections
- Skin and soft tissue infections
- Urinary tract infections
- Joint infections
- Meningitis
Contraindications
Do not use Efmerin if:
- There is a known allergy to ceftriaxone or other cephalosporins.
- Caution is advised in patients with a history of gastrointestinal diseases.
Side Effects
Common side effects of Efmerin may include:
- Diarrhea
- Nausea
- Injection site reactions
- Allergic reactions
Usage Instructions
Dosage: The usual adult dose is 1 to 2 grams given once or twice daily. Dosage may vary based on the condition being treated. Follow the healthcare provider’s instructions for proper administration.
Benefits Compared to Analogues
Efmerin offers the advantage of a broad spectrum of antibacterial activity compared to some other antibiotics. It is effective against many types of bacteria, reducing the need for multiple medications in certain infections.
Suitable Patient Groups
Efmerin is suitable for use in both adult and pediatric populations. Dosage adjustments may be necessary based on age and weight. Caution is advised when administering to elderly patients or those with renal impairment.
Storage and Shelf Life
Store Efmerin as directed on the packaging. Check the expiration date before use and do not use if expired. Keep out of reach of children.
Packaging Description
Each vial of Efmerin contains 1g of ceftriaxone powder for reconstitution. The packaging should include instructions for proper reconstitution and administration.
Clinical Evidence and Proven Effectiveness
Pharmacological Effects: Ceftriaxone, the active ingredient in Efmerin, has been shown to be effective in inhibiting bacterial growth by disrupting cell wall synthesis.
Clinical studies have demonstrated the efficacy of ceftriaxone in treating various infections. For example, a study published in the Journal of Antimicrobial Chemotherapy highlighted the successful treatment of pneumonia with ceftriaxone.
Additional Information
It is crucial to complete the full course of treatment with Efmerin as prescribed, even if symptoms improve. Failure to do so may result in incomplete eradication of the infection and potential resistance development.
Prior to using Efmerin, inform your healthcare provider about any existing medical conditions, ongoing medications, and allergies to ensure safe and effective treatment.
