Description
Enalozid (Enalapril, Hydrochlorothiazide) Tablets 12.5 mg. №30
Ingredients
Active substances: Enalapril, Hydrochlorothiazide
Mechanism of Action
Pharmacological Effects: Enalapril inhibits the angiotensin-converting enzyme, leading to vasodilation and reduced aldosterone secretion. Hydrochlorothiazide promotes diuresis by inhibiting sodium reabsorption in the distal convoluted tubule.
Indications for Use
Enalozid tablets are indicated for the treatment of hypertension in patients whose blood pressure is not adequately controlled with monotherapy.
Contraindications
Do not use Enalozid tablets if you are allergic to any of the ingredients, have a history of angioedema related to previous treatment with ACE inhibitors, or if you are pregnant.
Side Effects
Common side effects of Enalozid tablets may include dizziness, dry cough, hypotension, electrolyte imbalances, and renal dysfunction. Contact your healthcare provider if you experience any severe or persistent side effects.
Usage Instructions
Take Enalozid tablets orally with or without food, as directed by your healthcare provider. The recommended dose is 1 tablet once a day.
Benefits Compared to Analogues
Enalozid tablets offer the advantage of combining the proven efficacy of enalapril and hydrochlorothiazide in a single formulation, leading to better blood pressure control and potential cardiovascular risk reduction compared to monotherapy.
Suitable Patient Groups
Enalozid tablets are suitable for adult patients with hypertension. Dosage adjustment may be necessary for elderly patients or those with renal impairment. The safety and efficacy of this medication in children have not been established.
Storage and Shelf Life
Store Enalozid tablets in a cool, dry place away from direct sunlight. Keep the tablets in their original packaging to protect them from moisture. Check the expiration date on the packaging and do not use the tablets if expired.
Packaging Description
Each package of Enalozid tablets contains 30 tablets of 12.5 mg strength. The tablets are sealed in blister packs to ensure their integrity and potency.
Clinical Evidence and Proven Effectiveness
Enalapril and hydrochlorothiazide have been extensively studied for their efficacy in hypertension management. Clinical trials have demonstrated that the combination therapy leads to a significant reduction in blood pressure and cardiovascular events. A meta-analysis published in the Journal of Hypertension confirmed the safety and efficacy of enalapril and hydrochlorothiazide combination in hypertensive patients.
