Description

Esmeron (rocuronium bromide) solution for injections 10 mg/ml. 5 ml. (50 mg.) vial №10

Ingredients:

Each vial contains 50 mg of rocuronium bromide in a 5 ml solution for injections.

Dosage:

The dosage of Esmeron should be individualized based on the patient’s weight, age, and medical condition. It is typically administered intravenously and the recommended initial dose is 0.6 mg/kg.

Indications:

Esmeron is indicated for use as an adjunct to general anesthesia to facilitate tracheal intubation and provide skeletal muscle relaxation during surgery or mechanical ventilation.

Contraindications:

Esmeron is contraindicated in patients with known hypersensitivity to rocuronium bromide or any of the ingredients in the formulation. It should not be used in patients with a history of malignant hyperthermia.

Directions:

Esmeron should only be administered by healthcare professionals trained in the use of neuromuscular blocking agents. The injection should be given slowly over 5-10 seconds.

Scientific Evidence:

Studies have shown that Esmeron is effective in providing skeletal muscle relaxation for intubation and surgery. Research published in the Journal of Anesthesia and Clinical Research demonstrated the rapid onset and reliable action of rocuronium bromide in clinical settings.

Additional Information:

Esmeron has a rapid onset of action and a short duration of effect, making it a valuable tool for anesthesiologists and critical care physicians. It is important to monitor the patient’s neuromuscular function during and after administration to ensure proper dosing and recovery.

Pharmacologically, Esmeron works by competitively binding to the nicotinic acetylcholine receptors at the neuromuscular junction, thereby blocking the action of acetylcholine and preventing muscle contraction. This results in muscle relaxation, facilitating intubation and surgical procedures.

Clinical trials have compared the effectiveness of Esmeron with other neuromuscular blocking agents and have shown favorable outcomes in terms of onset time, duration of action, and hemodynamic stability. These findings support the use of Esmeron as a reliable muscle relaxant in various clinical scenarios.