Description

Esmeron (rocuronium bromide) Solution for Injections 10 mg/ml, 5 ml Vial Pack of 10

Ingredients:

Each vial contains 50 mg of rocuronium bromide in a 5 ml solution for injections.

Mechanism of Action:

Esmeron competitively binds to the nicotinic acetylcholine receptors at the neuromuscular junction, blocking the action of acetylcholine and leading to muscle relaxation, which aids in tracheal intubation and surgical procedures.

Pharmacological Properties:

Esmeron acts as a neuromuscular blocking agent by inhibiting muscle contractions through its interaction with acetylcholine receptors.

Indications for Use:

Esmeron is indicated as an adjunct to general anesthesia to facilitate tracheal intubation and provide skeletal muscle relaxation during surgery or mechanical ventilation.

Contraindications:

Esmeron is contraindicated in patients with known hypersensitivity to rocuronium bromide or any components of the formulation. It should be avoided in individuals with a history of malignant hyperthermia.

Side Effects:

Common side effects of Esmeron may include hypotension, tachycardia, bronchospasm, and allergic reactions. Monitoring for these adverse effects is essential during administration.

Usage Instructions:

Esmeron dosing should be individualized based on the patient’s weight, age, and clinical status. The recommended initial dose is 0.6 mg/kg administered intravenously. Healthcare professionals experienced in neuromuscular blockade should administer Esmeron slowly over 5-10 seconds.

Benefits Compared to Analogues:

Esmeron offers rapid onset and reliable muscle relaxation, making it a preferred choice for anesthesiologists and critical care providers. Its short duration of action allows for precise control during procedures.

Suitable Patient Groups:

Esmeron is suitable for adult patients undergoing surgical interventions requiring tracheal intubation and muscle relaxation. Dosage adjustments may be necessary for pediatric and elderly populations based on individual characteristics.

Storage and Shelf Life:

Esmeron should be stored at controlled room temperature away from light and moisture. The shelf life of the product should be checked before each use, and expired vials should be discarded appropriately.

Packaging Description:

Esmeron is supplied in vials containing 50 mg of rocuronium bromide in a 5 ml solution for injections. Each pack consists of 10 vials for clinical use.

Clinical Evidence and Proven Effectiveness:

Studies have demonstrated the efficacy of Esmeron in providing rapid and reliable muscle relaxation for tracheal intubation and surgical procedures. Research published in the Journal of Anesthesia and Clinical Research highlighted the favorable onset time and action duration of rocuronium bromide in clinical practice.