Description
Fareston Tablets 20 mg. №30 Vial
Ingredients
Fareston tablets contain 20 mg of the active ingredient toremifene citrate. Other ingredients include lactose, magnesium stearate, microcrystalline cellulose, and colloidal silicon dioxide.
Mechanism of Action
Pharmacological Effects: Fareston works by blocking the effects of estrogen in breast tissue, thereby slowing or stopping the growth of cancer cells. It is a selective estrogen receptor modulator (SERM) that competitively inhibits estrogen binding to its receptor.
Indications
Fareston is indicated for the treatment of advanced breast cancer in postmenopausal women with estrogen-receptor-positive tumors.
Contraindications
Do not use Fareston if you are allergic to toremifene or any other ingredients in the tablets. It is also contraindicated in pregnant and breastfeeding women.
Side Effects
Common side effects of Fareston may include hot flashes, sweating, nausea, and vaginal discharge. Rare but serious side effects may include blood clots, stroke, and liver problems. Contact your healthcare provider if you experience any severe side effects.
Usage Instructions
Directions: Take Fareston orally with or without food. Swallow the tablets whole with a glass of water. Do not crush or chew the tablets.
Dosage: The recommended dosage of Fareston is 60 mg (3 tablets) taken once daily. It is important to follow the dosage instructions provided by your healthcare provider.
Benefits Compared to Analogues
Fareston offers a comparable efficacy to other selective estrogen receptor modulators (SERMs) with a potentially favorable side effect profile in the treatment of advanced breast cancer.
Suitable Patient Groups
Fareston is suitable for postmenopausal women with estrogen-receptor-positive advanced breast cancer. It is not recommended for use in pregnant or breastfeeding women.
Storage and Shelf Life
Store Fareston tablets in a cool, dry place away from direct sunlight. Keep the medication out of reach of children. Check the expiration date on the packaging and do not use the tablets if expired.
Packaging Description
Fareston tablets are supplied in a vial containing 30 tablets of 20 mg each. The vial is sealed for protection and should be kept closed when not in use.
Scientific Evidence
Studies have shown that Fareston is effective in the treatment of advanced breast cancer. Research published in the Journal of Clinical Oncology demonstrated the efficacy of toremifene in reducing tumor size and improving overall survival rates in patients.
Clinical Trials
Clinical trials have shown that Fareston is well-tolerated and effective in postmenopausal women with advanced breast cancer. A study published in Breast Cancer Research and Treatment reported a significant reduction in tumor size and a favorable safety profile in patients treated with toremifene.
Additional Information
It is important to regularly monitor liver function tests while taking Fareston, as the medication can affect liver enzymes. Inform your healthcare provider of any liver problems or other medical conditions before starting treatment.
