$24.00
Manufacturer: Germany
Disinfection of the skin of the hands of medical personnel, treatment of the skin of the hands of medical staff before and after performing medical manipulations. Cutting skin areas affected by staphylococcal and streptococcal impetigo, and areas bordering them. Decontamination of the skin of the hands in all cases associated with an increased risk of infection and the spread of harmful microorganisms. Treatment of microtrauma of the skin. Hygienic disinfection of the skin.
Description
GOROSTEN COMPOSITION
active substance: decamethoxin
1 ml 0.25 mg decamethoxin
Excipients: ethanol 96%, glycerin, alcohol citral solution 1%, water for injection.
GOROSTEN DOSAGE FORM
Solution for external use.
GOROSTEN MAIN PHYSICAL AND CHEMICAL PROPERTIES
colorless, slightly opalescent liquid with a lemon scent.
PHARMACOLOGICAL GROUP
Antiseptic and disinfectants. Quaternary ammonium compounds. ATX code D08A J.
PHARMACOLOGICAL PROPERTIES
Pharmacological
Antiseptic preparation Gorosten has antimicrobial, antiviral, antifungal effects. The action of decamethoxin is based on the effect on the membranes of the microbial cell: decamethoxin destroys the supra-membrane layer, loosens the membrane, increases its permeability to large-molecular substances. Since most of the enzymes are fixed on the membrane structures, decamethoxin changes the enzymatic activity of the cell, suppressing the enzymatic systems. The hydrophobic radical decamethoxin promotes maximum binding of the drug to the cell membrane of microorganisms. The cationic radical decamethoxin first reduces and then neutralizes the charge of the microbial cell wall. Decamethoxin does not affect the membranes of human cells, since they have a significantly longer length of lipid radicals, so there is no hydrophobic interaction with them. Decamethoxin has a pronounced bactericidal effect on gram-positive, gram-negative aerobic and anaerobic microorganisms: staphylococci, streptococci, diphtheria and Escherichia coli, Salmonella, Proteus, Klebsiella, Shigella, Pseudomonas, Clostridia, Campylobacterium, Mycoplasma, Glamydia. Decamethoxin also acts as a fungicide against yeast-like fungi, causative agents of epidermophytosis, trichophytosis, microsporia, some types of mold fungi (aspergillus, penicia), has a virucidal effect on lipophilic viruses, including AIDS, hepatitis.
Gorosten is highly active against antibiotic-resistant microorganisms (penicillin, chloramphenicol, tetracycline, streptomycin, gentamicin, neomycin, novobiocin, oleandomycin, cephalosporins, fluoroquinolones).
The formation of strains of microorganisms resistant to the Gorosten drug does not occur with prolonged use of the drug. Bacteriostatic (fungistatic) concentrations are similar to its bactericidal (fungicidal), virucidal, sporicidal concentrations.
In the process of using the drug Gorosten, the sensitivity of antibiotic-resistant microorganisms to antibiotics increases.
Pharmacokinetics.
The drug is practically not absorbed by mucous membranes, skin and wound surface, and does not stain the skin, and citral gives it a pleasant lemon scent.
INDICATIONS
Disinfection of the skin of the hands of the personnel of medical institutions, treatment of the skin of the hands of the medical personnel before and after performing medical procedures.
Treatment of skin areas affected by staphylococcal and streptococcal impetigo and areas adjacent to them.
Disinfection of the skin of the hands, in all cases associated with an increased risk of infection and spread of microorganisms hazardous to health.
Treatment of skin microtraumas.
Hygienic skin disinfection.
CONTRAINDICATIONS
Sensitivity to drug components.
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